Guest of the League
| Away | Home | Time | Away Probable | Home Probable | Status | |||
|---|---|---|---|---|---|---|---|---|
 | Blue Jays | at |  | Cubs | 2:20pm ET | Gausman R (4-5) | Brown R (4-2) | |
 | White Sox | at |  | Tigers | 6:40pm ET | Eisert L (1-0) | Skubal L (3-3) | 6:40pm |
 | Reds | at |  | Yankees | 7:05pm ET | Lowder R (3-3) | Schlittler R (7-3) | 7:05pm |
 | Giants | at |  | Marlins | 7:10pm ET | Roupp R (5-7) | Bachar R (0-0) | 7:10pm |
 | Nationals | at |  | Rays | 7:10pm ET | Poulin L (3-0) | Jax R (1-5) | 7:10pm |
 | Brewers | at |  | Braves | 7:15pm ET | Misiorowski R (8-2) | Perez L (5-4) | 7:15pm |
 | Padres | at |  | Rangers | 8:05pm ET | Vasquez R (6-4) | deGrom R (5-4) | 8:05pm |
 | Guardians | at |  | Astros | 8:10pm ET | Bibee R (2-7) | Imai R (3-3) | 8:10pm |
 | Cardinals | at |  | Royals | 8:15pm ET | McGreevy R (3-5) | Lugo R (2-4) | 8:15pm |
 | Pirates | at |  | Rockies | 8:40pm ET | Chandler R (2-7) | Freeland L (1-7) | 8:40pm |
 | Angels | at |  | Athletics | 9:40pm ET | Soriano R (8-4) | Springs L (3-7) | 9:40pm |
 | Twins | at |  | Diamondbacks | 9:45pm ET | Prielipp (2-4) | Soroka R (8-3) | 9:45pm |
 | Red Sox | at |  | Mariners | 10:10pm ET | Suarez L (2-3) | Miller R (3-0) | 10:10pm |
 | Orioles | at |  | Dodgers | 10:10pm ET | Gibson R (1-2) | Sasaki R (3-4) | 10:10pm |
