| PIT | Tsung-Che Cheng | The Pittsburgh Pirates designated INF Tsung-Che Cheng for assignment. |
| ARI | Ildemaro Vargas | The Arizona Diamondbacks signed INF Ildemaro Vargas to a minor league contract. |
| ATL | Ian Hamilton | The Atlanta Braves signed RHP Ian Hamilton. |
| PIT | Marco Luciano | The Pittsburgh Pirates designated OF Marco Luciano for assignment. |
| SF | Wade Meckler | The San Francisco Giants designated OF Wade Meckler for assignment. |
| NYM | Brandon Waddell | The New York Mets sent LHP Brandon Waddell outright to the minors. |
| ATL | Anthony Molina | The Atlanta Braves sent RHP Anthony Molina outright to the minors. |
| WSH | Warming Bernabel | The Washington Nationals signed INF Warming Bernabel to a minor league contract. |
| SD | Jose Miranda | The San Diego Padres signed INF Jose Miranda to a minor league contract. |
| TB | Osvaldo Bido | The Tampa Bay Rays claimed RHP Osvaldo Bido off waivers from the Atlanta Braves. |
| BAL | Josh Walker | The Baltimore Orioles designated LHP Josh Walker for assignment. |
| STL | Matt Koperniak | The St. Louis Cardinals sent OF Matt Koperniak outright to the minors. |
| BAL | Shane Baz | The Tampa Bay Rays traded RHP Shane Baz to the Baltimore Orioles. |
| TB | Jacob Melton | The Houston Astros traded OF Jacob Melton to the Tampa Bay Rays. |
| HOU | Mike Burrows | The Pittsburgh Pirates traded RHP Mike Burrows to the Houston Astros. |
| PIT | Brandon Lowe | The Tampa Bay Rays traded INF Brandon Lowe to the Pittsburgh Pirates. |
| PIT | Mason Montgomery | The Tampa Bay Rays traded LHP Mason Montgomery to the Pittsburgh Pirates. |
| PHI | Kyle Backhus | The Arizona Diamondbacks traded LHP Kyle Backhus to the Philadelphia Phillies. |
| PIT | Jake Mangum | The Tampa Bay Rays traded OF Jake Mangum to the Pittsburgh Pirates. |
| KC | Abraham Toro | The Kansas City Royals signed INF Abraham Toro to a minor league contract. |
| BOS | Abraham Toro | INF Abraham Toro elected free agency. |
| KC | Matt Strahm | The Philadelphia Phillies traded LHP Matt Strahm to the Kansas City Royals. |
| LAD | Chuckie Robinson | The Los Angeles Dodgers signed C Chuckie Robinson to a minor league contract. |
| PHI | Jonathan Bowlan | The Kansas City Royals traded RHP Jonathan Bowlan to the Philadelphia Phillies. |
| NYY | Zack Short | The New York Yankees signed INF Zack Short to a minor league contract. |
