Brandon Woodruff threw six dominant innings in his return from injury and Joey Ortiz hit a go-ahead sacrifice fly on Monday to help the visiting Milwaukee Brewers earn a 2-1 victory in 10 innings over the Cincinnati Reds.

In his first start since April 30, having recovered from right shoulder inflammation, Woodruff retired the first 16 Reds he faced before allowing a one-out single in the sixth. The veteran right-hander struck out 10 and didn't issue a walk.

Ortiz snapped the scoreless tie with his fly ball off Tony Santillan (1-4). A wild pitch gave the Brewers a 2-0 edge. Joel Kuhnel allowed Sal Stewart's RBI groundout in the bottom of the inning but still secured his fifth save. Milwaukee reliever Trevor Megill (2-2) pitched the ninth inning.

Brady Singer threw seven scoreless innings for the Reds, who mustered just two hits and struck out 14 times.

Rockies 3, Red Sox 2

Jake McCarthy hit a walk-off three-run triple in the ninth inning, giving Colorado a win over Boston in Denver.

Colorado was held down by Boston rookie Jake Bennett for six innings but came through against Aroldis Chapman (0-3) in the ninth. Victor Vodnik (2-2) pitched two hitless, scoreless innings of relief, and Tyler Freeman had three hits for the Rockies, who have won three of their past four games.

The rally wiped away a strong start by Bennett, who allowed just four hits, struck out nine and didn't walk a batter. Willson Contreras and Caleb Durbin (2-for-3) had run-scoring hits in the sixth inning for the Red Sox, who took their sixth loss in eight games.

White Sox 6, Guardians 5

Sam Antonacci lined a game-ending, two-run single with two outs in the ninth inning to lift host Chicago past Cleveland, leaving the teams tied atop the American League Central after the series opener.

Antonacci went 2-for-4 with three RBIs and two stolen bases, and Braden Montgomery had two hits, two runs and an RBI. Chris Murphy (2-0) emerged with the victory.

Brayan Rocchio went 3-for-5 for the Guardians, and Kyle Manzardo capped a two-run ninth with a sacrifice fly. Cade Smith (2-1) couldn't hold the lead in the bottom of the ninth.

Padres 1, Braves 0

Manny Machado homered in the fourth inning and Michael King fired seven scoreless frames as San Diego blanked visiting Atlanta.

King (5-6) allowed six hits and walked none while fanning five in his first win since May 18. Adrian Morejon tossed a 1-2-3 eighth and Mason Miller worked around two-out trouble in the ninth to log his 21st save in as many chances.

Grant Holmes (4-4) gave up three hits and the game's only run in 4 2/3 innings. The Braves' Austin Riley went 3-for-4.

Dodgers 2, Twins 1

Shohei Ohtani and Freddie Freeman each hit a solo home run, and that proved to be enough as Los Angeles held on for a win over Minnesota in Minneapolis.

Alex Call and Tommy Edman added two hits apiece for the Dodgers, who snapped a two-game skid. Eric Lauer (3-5) did not allow a hit in six scoreless innings as the bulk reliever. Tanner Scott pitched a scoreless ninth inning to earn his 10th save.

Byron Buxton hit a solo home run for the Twins, who managed only three hits. Zebby Matthews (3-5) took a hard-luck loss despite yielding only two runs on six hits in six innings.

Royals 2, Rays 1

Michael Wacha allowed one run over seven strong innings, and Lane Thomas and Carter Jensen each had an RBI as Kansas City beat Tampa Bay in St. Petersburg, Fla.

Wacha (5-5) recorded his 11th quality start of the season, holding the Rays to six hits. Alex Lange pitched a perfect ninth for his sixth save.

Tampa Bay's Drew Rasmussen (6-4) was charged with two runs on four hits in six innings. Yandy Diaz, whose two-out RBI double in the fifth inning scored the Rays' lone run, extended his home on-base streak to 20 games.

Tigers 5, Yankees 3

Kevin McGonigle had two hits and drove in two runs, Framber Valdez pitched six strong innings and host Detroit extended its winning streak to four games with a victory over New York.

Valdez (4-5) limited the Yankees to one run and four hits while striking out eight and walking two. Will Vest recorded the last four outs for his second save.

Riley Greene hit a solo homer and scored twice for the Tigers, who have won four in a row. Amed Rosario homered for the Yankees, who have dropped three out of four. Gerrit Cole (2-2) was tagged for five runs on nine hits in 4 1/3 innings.

Blue Jays 4, Astros 2

Kazuma Okamoto homered and doubled to help Toronto defeat visiting Houston in the opener of a three-game series.

Vladimir Guerrero Jr. added two hits and an RBI for the Blue Jays, who earned their fifth win in six games. Braydon Fisher (3-2) threw 1 1/3 innings of scoreless relief for the win, and Louis Varland handled the ninth inning for his 16th save.

Isaac Paredes and Jose Altuve produced RBI singles for the Astros, who had won four of their previous five games. Houston reliever Enyel De Los Santos (0-2) gave up the tiebreaking run in the seventh inning.

Cardinals 3, Diamondbacks 2

Host St. Louis got another strong outing from starter Andre Pallante en route to a win over Arizona.

Pallante (9-4) spread six hits across six innings, allowing just one run to win his fourth consecutive start. He outdueled Merrill Kelly (5-7), who also made it through six but gave up three runs on seven hits in the process.

Alec Burleson, Blaze Jordan and Nathan Church had the RBIs for the Cardinals, who took the opener of a four-game set. Tommy Troy homered and Ketel Marte and Corbin Carroll added two hits apiece for the Diamondbacks, who finished 0-for-8 with runners in scoring position.

Nationals 4, Phillies 1

Foster Griffin pitched 7 1/3 strong innings and host Washington beat Philadelphia.

Luis Garcia Jr. and Curtis Mead homered while Dylan Crews, James Wood and Keibert Ruiz each had a double and a single for the Nationals. Griffin (8-2) gave up a run on four hits, and Clayton Beeter worked the ninth for his sixth save.

Brandon Marsh homered for the Phillies, who had won two straight and four of six. Tim Mayza (2-2) allowed one run in the first inning. Alan Rangel, recalled from Triple-A Lehigh Valley on Monday, then permitted a run on five hits over five innings.

Orioles 6, Angels 1

Kyle Bradish struck out nine over eight shutout innings and Taylor Ward and Coby Mayo homered to lead Baltimore past Los Angeles in Anaheim, Calif.

Bradish (5-7), a fourth-round draft pick of the Angels in 2018, scattered six singles and one walk in his first-ever appearance at Anaheim Stadium. Gunnar Henderson tripled and had three hits for the Orioles, who won their third straight game.

Jorge Soler homered and Nolan Schanuel had two hits for the Angels, who had a two-game winning streak end. Sam Aldegheri (2-3) gave up five runs on five hits over 4 2/3 innings.

Rangers 4, Marlins 3

Alejandro Osuna hit a go-ahead double in the eighth inning as Texas won at Miami, snapping the Marlins' eight-game home winning streak.

Ezequiel Duran slugged a two-run homer while Brandon Nimmo went 3-for-3 for the Rangers. Robby Ahlstrom (2-0) threw one scoreless inning in relief, and Jacob Latz recorded four outs for his 14th save.

Miami's Otto Lopez went 2-for-3 to raise his major-league-leading batting average to .336. Xavier Edwards had a single and a triple. Marlins reliever Calvin Faucher (4-4) allowed two runs in one frame.