Guest of the League
Lineup Changes
7 -
| Started U | Josh Lowe (OF) TB | Owner | Mon May 6 5:35pm ET |
| Benched | Esteury Ruiz (OF) OAK | Owner | Mon May 6 5:35pm ET |
| Started P | Yu Darvish (P) SD | Owner | Sat May 4 11:52am ET |
| Benched | Chris Bassitt (P) TOR | Owner | Sat May 4 11:52am ET |
BL 303 - James Nicola
| Benched | Will Benson (OF) CIN | Owner | Mon May 6 10:11am ET |
| Started OF | Jacob Young (OF) WSH | Owner | Mon May 6 10:11am ET |
| Started P | Tyler Anderson (P) LAA | Owner | Mon May 6 4:38am ET |
| Benched | Evan Phillips (P) LAD | Owner | Mon May 6 4:38am ET |
| Started P | John Means (P) BAL | Owner | Mon May 6 4:38am ET |
| Started P | Luis Gil (P) NYY | Owner | Mon May 6 4:38am ET |
| Started U | Jorge Polanco (2B, 3B, MI, CI) SEA | Owner | Sun May 5 12:29pm ET |
| Benched | Jacob Young (OF) WSH | Owner | Sun May 5 12:29pm ET |
Club 21 - Frank Civitella
| Benched | Kevin Ginkel (P) ARI | Owner | Tue May 7 5:01pm ET |
| Started P | Paul Sewald (P) ARI | Owner | Tue May 7 5:01pm ET |
| Started P | Kevin Ginkel (P) ARI | Owner | Mon May 6 1:37pm ET |
| Benched | Kevin Gausman (P) TOR | Owner | Mon May 6 1:37pm ET |
| Started P | Paul Blackburn (P) OAK | Owner | Mon May 6 1:36pm ET |
| Benched | Lance Lynn (P) STL | Owner | Mon May 6 1:36pm ET |
| Started P | Jameson Taillon (P) CHC | Owner | Mon May 6 1:36pm ET |
| Started OF | Mark Canha (1B, CI, OF) DET | Owner | Mon May 6 1:36pm ET |
| Started OF | Connor Joe (1B, CI, OF) PIT | Owner | Mon May 6 7:00am ET |
| Benched | Tanner Scott (P) MIA | Owner | Sun May 5 12:55pm ET |
| Started P | Marcus Stroman (P) NYY | Owner | Sun May 5 12:55pm ET |
| Benched | Tanner Bibee (P) CLE | Owner | Sun May 5 12:55pm ET |
| Started P | Kevin Gausman (P) TOR | Owner | Sun May 5 12:55pm ET |
| Started P | Tanner Bibee (P) CLE | Owner | Fri May 3 6:19pm ET |
| Benched | Bailey Falter (P) PIT | Owner | Fri May 3 6:19pm ET |
Count Me In - Lee Polillo
| Started CI | Tyler Nevin (1B, 3B, CI, OF) OAK | Owner | Mon May 6 12:03pm ET |
| Benched | Tyler Black (2B, MI) MIL | Owner | Mon May 6 12:03pm ET |
| Started 2B | Jose Altuve (2B, MI) HOU | Owner | Mon May 6 12:03pm ET |
| Started 2B | Tyler Black (2B, MI) MIL | Owner | Mon May 6 12:02pm ET |
| Benched | Jose Altuve (2B, MI) HOU | Owner | Mon May 6 12:02pm ET |
| Started 2B | Jose Altuve (2B, MI) HOU | Owner | Mon May 6 12:02pm ET |
| Benched | Tyler Black (2B, MI) MIL | Owner | Mon May 6 12:02pm ET |
| Started 2B | Tyler Black (2B, MI) MIL | Owner | Mon May 6 12:02pm ET |
| Benched | Jose Altuve (2B, MI) HOU | Owner | Mon May 6 12:02pm ET |
| Started SS | Ezequiel Tovar (SS, MI) COL | Owner | Mon May 6 10:03am ET |
| Benched | Trea Turner (SS, MI) PHI | Owner | Mon May 6 10:03am ET |
| Benched | Tarik Skubal (P) DET | Owner | Mon May 6 9:58am ET |
| Started P | Tyler Glasnow (P) LAD | Owner | Mon May 6 9:58am ET |
| Started P | David Bednar (P) PIT | Owner | Mon May 6 9:58am ET |
| Benched | Tyler Glasnow (P) LAD | Owner | Mon May 6 9:58am ET |
| Started P | Triston McKenzie (P) CLE | Owner | Mon May 6 9:57am ET |
| Benched | Aaron Civale (P) TB | Owner | Mon May 6 9:57am ET |
| Started P | Cole Ragans (P) KC | Owner | Mon May 6 9:56am ET |
| Benched | David Bednar (P) PIT | Owner | Mon May 6 9:56am ET |
| Started P | Aaron Civale (P) TB | Owner | Sat May 4 9:32am ET |
| Benched | MacKenzie Gore (P) WSH | Owner | Sat May 4 9:32am ET |
Fleshmonkey - Martin Amos
| Started OF | Brent Rooker (OF) OAK | Owner | Mon May 6 10:12am ET |
| Benched | Joel Payamps (P) MIL | Owner | Mon May 6 9:48am ET |
| Started P | Andrew Abbott (P) CIN | Owner | Mon May 6 9:48am ET |
| Benched | Grayson Rodriguez (P) BAL | Owner | Mon May 6 9:47am ET |
| Started P | Kutter Crawford (P) BOS | Owner | Mon May 6 9:47am ET |
Kill or Be Killed - Joseph Walsh
| No starting lineup changes performed this week. |
Pine Apple - TYLER MURRAY
| Benched | Byron Buxton (OF) MIN | Owner | Mon May 6 1:59pm ET |
| Started OF | Willi Castro (2B, SS, 3B, MI, CI, OF) MIN | Owner | Mon May 6 1:59pm ET |
Posers -
| Benched | Nathan Eovaldi (P) TEX | Owner | Mon May 6 1:34pm ET |
| Started P | Cole Irvin (P) BAL | Owner | Mon May 6 1:34pm ET |
| Started P | Hector Neris (P) CHC | Owner | Mon May 6 1:31pm ET |
VP23 - VINNIE PORCELLINI
| Benched | James Paxton (P) LAD | Owner | Mon May 6 4:59am ET |
| Started P | Jon Gray (P) TEX | Owner | Mon May 6 4:59am ET |
| Started P | Walker Buehler (P) LAD | Owner | Mon May 6 4:59am ET |
| Benched | Jason Foley (P) DET | Owner | Mon May 6 4:59am ET |
| Benched | Jordan Montgomery (P) ARI | Owner | Mon May 6 4:58am ET |
| Started P | Justin Steele (P) CHC | Owner | Mon May 6 4:58am ET |
You're Done Alvarez - Michael
| Started C | Danny Jansen (C) TOR | Owner | Mon May 6 1:29pm ET |
| Started P | Dean Kremer (P) BAL | Owner | Mon May 6 1:28pm ET |
| Started P | Kyle Bradish (P) BAL | Owner | Mon May 6 1:28pm ET |
| Started CI | Jordan Westburg (2B, 3B, MI, CI) BAL | Owner | Mon May 6 1:28pm ET |
| Benched | Christian Encarnacion-Strand (1B, CI) CIN | Owner | Mon May 6 1:28pm ET |
| Started MI | Luis Garcia Jr. (2B, MI) WSH | Owner | Mon May 6 1:28pm ET |
| Benched | Blaze Alexander (SS, MI) ARI | Owner | Mon May 6 1:28pm ET |
