Guest of the League
Lineup Changes
Ace Of Clubs - Tom & Aaron Smith
| Started C | Mitch Garver (C) SEA | Owner | Mon May 6 11:30am ET |
| Started C | Patrick Bailey (C) SF | Owner | Mon May 6 3:49am ET |
| Started OF | Mark Canha (1B, CI, OF) DET | Owner | Mon May 6 3:49am ET |
| Benched | Martin Perez (P) PIT | Owner | Tue Apr 30 11:47pm ET |
| Started P | Jhoan Duran (P) MIN | Owner | Tue Apr 30 11:47pm ET |
Bums23 - Ray Quist
| Started OF | Brent Rooker (OF) OAK | Owner | Mon May 6 10:16am ET |
| Started OF | Jo Adell (OF) LAA | Owner | Mon May 6 10:16am ET |
| Started P | Triston McKenzie (P) CLE | Owner | Mon May 6 8:11am ET |
| Benched | Reid Detmers (P) LAA | Owner | Mon May 6 8:11am ET |
| Started P | Sean Manaea (P) NYM | Owner | Mon May 6 8:11am ET |
| Benched | Grayson Rodriguez (P) BAL | Owner | Mon May 6 8:11am ET |
| Started U | Jake Burger (3B, CI) MIA | Owner | Mon May 6 8:10am ET |
Griffins11 BL313 - David Foster
| Benched | Nathan Eovaldi (P) TEX | Owner | Mon May 6 8:59am ET |
| Started P | Gavin Stone (P) LAD | Owner | Mon May 6 8:59am ET |
| Started CI | Alex Bregman (3B, CI) HOU | Owner | Mon May 6 8:58am ET |
| Benched | Christian Encarnacion-Strand (1B, CI) CIN | Owner | Mon May 6 8:58am ET |
Hackers - David Glatt
| Started P | Justin Verlander (P) HOU | Owner | Mon May 6 2:10pm ET |
| Benched | Christian Scott (P) NYM | Owner | Mon May 6 2:10pm ET |
| Benched | Jordan Montgomery (P) ARI | Owner | Mon May 6 4:28am ET |
| Started P | Christian Scott (P) NYM | Owner | Mon May 6 4:28am ET |
| Benched | Justin Verlander (P) HOU | Owner | Mon May 6 4:26am ET |
| Started P | Jordan Montgomery (P) ARI | Owner | Mon May 6 4:26am ET |
| Benched | Marcus Stroman (P) NYY | Owner | Mon May 6 4:26am ET |
| Started P | Kyle Bradish (P) BAL | Owner | Mon May 6 4:26am ET |
| Started OF | Joey Loperfido (OF) HOU | Owner | Mon May 6 4:25am ET |
Intrascrotal Hematoma - Jerry Penrod
| Started P | Jameson Taillon (P) CHC | Owner | Mon May 6 12:02pm ET |
| Benched | Robert Suarez (P) SD | Owner | Mon May 6 12:02pm ET |
| Started OF | Jurickson Profar (OF) SD | Owner | Mon May 6 12:01pm ET |
| Started P | Yu Darvish (P) SD | Owner | Fri May 3 12:18pm ET |
| Benched | Alexis Diaz (P) CIN | Owner | Fri May 3 12:18pm ET |
Morries Wigs - Emilio Cutaneo
| Started P | Garrett Crochet (P) CWS | Owner | Mon May 6 9:06am ET |
| Benched | Aaron Civale (P) TB | Owner | Mon May 6 9:06am ET |
| Benched | Brenton Doyle (OF) COL | Owner | Mon May 6 9:05am ET |
| Started OF | Andy Pages (OF) LAD | Owner | Mon May 6 9:05am ET |
| Started OF | Oswaldo Cabrera (3B, CI, OF) NYY | Owner | Sun May 5 8:44pm ET |
| Started 3B | Jose Ramirez (3B, CI) CLE | Owner | Sun May 5 8:44pm ET |
| Started CI | Nathaniel Lowe (1B, CI) TEX | Owner | Sun May 5 8:43pm ET |
| Benched | Jose Ramirez (3B, CI) CLE | Owner | Sun May 5 8:43pm ET |
| Benched | Michael Busch (1B, 3B, CI) CHC | Owner | Sun May 5 8:43pm ET |
| Benched | Oswaldo Cabrera (3B, CI, OF) NYY | Owner | Sun May 5 8:43pm ET |
| Started OF | Brenton Doyle (OF) COL | Owner | Sun May 5 8:43pm ET |
| Benched | Mike Trout (OF) LAA | Owner | Sun May 5 8:43pm ET |
Nailer2 -
| Started C | Danny Jansen (C) TOR | Owner | Mon May 6 10:22am ET |
| Started SS | Ha-Seong Kim (2B, SS, 3B, MI, CI) SD | Owner | Mon May 6 10:16am ET |
| Benched | Trea Turner (SS, MI) PHI | Owner | Mon May 6 10:16am ET |
| Benched | Ha-Seong Kim (2B, SS, 3B, MI, CI) SD | Owner | Mon May 6 10:16am ET |
| Started MI | Luis Garcia Jr. (2B, MI) WSH | Owner | Mon May 6 10:16am ET |
| Started P | Taj Bradley (P) TB | Owner | Mon May 6 7:04am ET |
| Benched | Edward Cabrera (P) MIA | Owner | Sat May 4 8:44am ET |
| Started P | Walker Buehler (P) LAD | Owner | Sat May 4 8:44am ET |
| Started U | Colton Cowser (OF) BAL | Owner | Sat May 4 8:43am ET |
| Benched | Byron Buxton (OF) MIN | Owner | Sat May 4 8:43am ET |
Pockets 504 - James Nicola
| Started P | Dean Kremer (P) BAL | Owner | Mon May 6 4:55am ET |
| Benched | Mitchell Parker (P) WSH | Owner | Mon May 6 4:55am ET |
| Benched | Joe Musgrove (P) SD | Owner | Sun May 5 6:07pm ET |
| Started P | Mitchell Parker (P) WSH | Owner | Sun May 5 6:07pm ET |
| Benched | Evan Phillips (P) LAD | Owner | Sun May 5 2:54pm ET |
| Started P | Reese Olson (P) DET | Owner | Sun May 5 2:54pm ET |
Sheneedmilk - Zack McKeown
| No starting lineup changes performed this week. |
VINNIEP23 - VINNIE PORCELLINI
| Benched | MacKenzie Gore (P) WSH | Owner | Mon May 6 4:54am ET |
| Started P | Brady Singer (P) KC | Owner | Mon May 6 4:54am ET |
| Benched | Luis Severino (P) NYM | Owner | Mon May 6 4:53am ET |
| Started P | Justin Steele (P) CHC | Owner | Mon May 6 4:53am ET |
