Teoscar Hernandez followed Jason Heyward's grand slam with a three-run homer in a seven-run ninth inning as the Los Angeles Dodgers rallied to beat the Colorado Rockies 11-9 on Tuesday in Denver.

It was the first time the Dodgers rallied from a five-run deficit in the ninth to win since July 18, 1957, when Brooklyn defeated the St. Louis Cardinals 10-9 in 11 innings.

The Rockies led 9-4 entering the ninth, but Colorado reliever Tyler Kinley loaded the bases with one out on two walks and a single. Heyward, pinch-hitting for Chris Taylor, homered off the foul pole in right to cut the deficit to one.

There were two runners on and two out when Hernandez homered to put Los Angeles ahead. Earlier, Ohtani socked a 476-foot homer, the longest hit in the majors this season.

Reds 2, Pirates 1

Santiago Espinal hit a two-run homer and Nick Lodolo tossed seven strong innings to win his fifth consecutive start as Cincinnati won at Pittsburgh.

Lodolo (8-2) allowed one run on four hits with no walks and eight strikeouts. Jonathan India and Luke Maile had two hits apiece for Cincinnati, which snapped a three-game losing streak and avenged a 4-1 loss on Monday in the opener of the three-game series.

Lodolo outdueled Pirates starter Bailey Falter (3-5), who yielded two runs on seven hits over seven innings. He walked two and struck out three. Bryan Reynolds singled and doubled for Pittsburgh to extend his hitting streak to 16 games, which is the longest active streak in the majors.

Mets 7, Rangers 6

Pete Alonso drilled a tiebreaking double in the ninth inning and New York stretched its winning streak to a season-high seven games with a comeback victory in Arlington, Texas.

Francisco Alvarez had three hits, including a tying two-run double, as New York recovered from a four-run deficit. Mark Vientos homered among three hits and Brandon Nimmo also went deep as the Mets won for the 13th time in their past 17 games.

Josh Smith hit a three-run homer and Wyatt Langford added a solo shot for Texas, which has lost five straight games and 10 of its past 14. Corey Seager drove in two runs for the Rangers.

Red Sox 4, Blue Jays 3

Ceddanne Rafaela had three hits, including a go-ahead, two-out RBI single in the eighth inning, and visiting Boston defeated Toronto.

Tyler O'Neill's home run to center leading off the eighth tied the game for the Red Sox, who have won the first two games of the three-game series and four straight overall. Zack Kelly (1-1) got the win with 1 1/3 innings of scoreless relief.

Toronto starter Chris Bassitt allowed two runs and seven hits in six innings. Brendon Little (0-1) took the loss, and Ernie Clement had two RBIs for Toronto.

Twins 7, Rays 6

Carlos Santana delivered a pinch-hit, walk-off single with two outs in the bottom of the ninth inning to lift Minnesota to a win over Tampa Bay in Minneapolis.

Santana's two-out hit drove in Manuel Margot, who led off the inning with a single and advanced to second base on a single by Carlos Correa. Willi Castro finished 2-for-4 with two doubles and three RBIs for the Twins, who won their sixth straight game.

Randy Arozarena hit a three-run homer to lead the Rays. Brandon Lowe and Josh Lowe added one solo home run apiece. Twins right-hander Jhoan Duran (3-2) earned the victory with a scoreless inning of relief.

Marlins 9, Cardinals 8 (10 innings)

Pinch hitter Vidal Brujan hit a walk-off single in the 10th inning as host Miami overcame four deficits to defeat St. Louis.

Jesus Sanchez went 3-for-5 with a homer and three RBIs for the Marlins, who ended a six-game losing streak.

Alec Burleson, Brendan Donovan and Paul Goldschmidt each homered for the Cardinals, who had won five of six.

Mariners 8, Guardians 5

J.P. Crawford homered and drove in three runs and Dylan Moore also went deep to go along with three runs, fueling Seattle over host Cleveland.

Luke Raley added a solo shot while Mitch Garver drove in two runs to propel the Mariners to their fourth win in a row and their 17th in the past 22 games. The power surge was more than enough for right-hander Bryce Miller (6-5), who allowed three runs (two earned) on six hits in 5 2/3 innings to improve to 3-0 in his past five starts.

Will Brennan had an RBI single among his three hits and Jose Ramirez added a run-scoring single for the Guardians, who have lost three straight games for the second time this season. They also dropped three straight from May 9-11.

Phillies 4, Padres 3

Nick Castellanos' fourth hit of the night was a walk-off double in the ninth inning, giving Philadelphia a come-from-behind victory over visiting San Diego.

Castellanos doubled twice, Kyle Schwarber added a home run and single and Brandon Marsh contributed two hits and an RBI for the Phillies, who strung together four straight hits in the ninth to erase a 3-2 deficit.

Luis Campusano hit a two-run homer for the Padres, who have dropped five straight.

Diamondbacks 5, Nationals 0

Ketel Marte hit a two-run homer and drove in three runs, Slade Cecconi tossed six strong innings and visiting Arizona beat Washington.

Joc Pederson had three hits for Arizona, which has won four of five.

Nationals starter Jake Irvin (5-6) allowed four runs on eight hits over five innings. He walked four, struck out two and was helped by his defense, which turned four double plays during his stint.

Yankees 4, Orioles 2

Aaron Judge scored on a base hit by Giancarlo Stanton in the third inning and exited an inning later with an injured left hand as host New York beat Baltimore in the opener of a three-game series between the top two teams in the American League.

Judge was hit on the left hand near his pinky and knuckle on a 1-2 fastball by Baltimore starter Albert Suarez (3-1) in the third. He stayed in the game after being briefly checked out, slid into third base on a base hit by Alex Verdugo and scored the Yankees' second run on Stanton's base hit. After the game, Judge said X-rays and a CT scan revealed no damage.

The Orioles avoided getting blanked for the third time this season thanks to a two-run homer by Anthony Santander in the ninth. Baltimore also lost Jordan Westburg to left hip discomfort after the top of the second inning.

Cubs 5, Giants 2

Dansby Swanson hit a two-run homer and Chicago scored three runs in the eighth to beat visiting San Francisco.

Ian Happ had two hits and two runs for the Cubs, while Michael Busch and Cody Bellinger each had two hits and one run in the middle game of the three-game series. Bellinger and Happ also drove in one run apiece for Chicago, which had lost two straight and four of its past five.

Curt Casali had a two-run double for the Giants. San Francisco starter Logan Webb allowed two runs and six hits in seven innings. He struck out five and walked one on 101 pitches.

Braves 2, Tigers 1

Rookie Spencer Schwellenbach threw six strong innings to earn his first major league win as Atlanta beat visiting Detroit for the second straight game.

Schwellenbach, a second-round draft pick in 2021, grew up in Saginaw, Mich., as a Tigers fan. The 24-year-old opened the outing with five scoreless innings before surrendering his lone run in the sixth. He allowed three hits and two walks and posted a career-best seven strikeouts.

The Braves have won five of their last six games, while the Tigers have lost three straight and dropped nine of their last 12. Detroit starter Casey Mize threw 87 pitches in four innings and allowed two runs on five hits, with no walks and three strikeouts.

White Sox 2, Astros 0

Rookie right-hander Jonathan Cannon pitched 8 2/3 shutout innings for his first career major league victory to lift host Chicago over Houston.

Cannon scattered seven hits and one walk with four strikeouts while reaching a career high in innings. Cannon (1-1) yielded consecutive soft singles with two outs in the ninth before yielding to John Brebbia, who retired Victor Caratini for the final out to earn the save.

Alex Bregman and Trey Cabbage had two hits each for the Astros. Houston starter Framber Valdez fell to 5-5 after allowing two runs and two hits in six innings. Valdez had five walks and five strikeouts.

Athletics 7, Royals 5

Zack Gelof homered, JJ Bleday collected three doubles and Oakland snapped a nine-game losing streak with a win over visiting Kansas City in the opener of a three-game series.

Gelof finished with two hits and two runs to complement his three RBIs for the A's, who outhit the Royals 11-7. Miguel Andujar also had two hits, while Max Schuemann also scored twice.

Salvador Perez had a pair of singles for the Royals, who lost for the seventh time in their past nine games.

Brewers 6, Angels 3

Tobias Myers threw 6 1/3 scoreless innings, but Milwaukee needed a game-saving catch by center fielder Sal Frelick in the bottom of the ninth to hold onto the victory over Los Angeles at Anaheim, Calif.

Behind Myers' performance, the Brewers took a 6-0 lead into the ninth. The Angels chipped away within 6-3, forcing Brewers manager Pat Murphy to summon closer Trevor Megill with two on and two outs.

Megill then yielded a drive to right-center by Taylor Ward. Frelick leaped and reached above the yellow line to make the catch, robbing Ward of what would have been a game-tying homer. Megill got his 14th save.