Manny Machado homered twice Saturday to help the San Diego Padres stretch their winning streak to five games with an 11-1 victory over the host Boston Red Sox.

Machado hit a two-run home run in the third inning and added a three-run homer in the fifth. He has 10 home runs this season. San Diego also received a solo home run from Jackson Merrill (his 12th blast of the season) and a two-run shot from Brett Sullivan (his first). The Padres have 20 home runs in their last 10 games.

Three of the four home runs came against Boston starter Tanner Houck (7-6), who turned 28 on Saturday. Houck had allowed two home runs in 103 1/3 innings this season entering Saturday's game. Houck surrendered eight runs (seven earned) on nine hits in 4 1/3 innings. He began the day leading the American League in ERA (2.18), but his ERA rose to 2.67.

San Diego starter Michael King (6-5) tossed six innings to earn the win. The right-hander gave up a run on five hits, struck out six and walked one. Jarren Duran accounted for Boston's run with his eighth homer, a solo shot in the sixth.

Dodgers 14, Giants 7 (11 innings)

Will Smith's tiebreaking two-run double and Jason Heyward's two-run triple keyed a seven-run explosion in the 11th inning that propelled visiting Los Angeles past San Francisco.

Smith's double to the fence off San Francisco's Sean Hjelle (3-2) got the uprising going. Freddie Freeman hit an RBI double and Chris Taylor added an RBI single before Heyward lashed his triple to right. Earlier, Shohei Ohtani clubbed his NL-best 26th homer of the season. Ryan Yarbrough pitched a perfect 11th in a non-save situation to secure a win for Daniel Hudson (5-1), who allowed the Giants' game-tying run in the 10th.

Matt Chapman went 3-for-5 for the Giants, who won Friday's series opener 5-3 on Brett Wisely's walk-off two-run homer.

Angels 6, Tigers 5 (10 innings)

Kevin Pillar hit an RBI single with one out in the 10th inning to lift Los Angeles to its sixth consecutive win by edging Detroit in Anaheim, Calif.

Taylor Ward began the inning as the automatic runner and moved to third on a sacrifice bunt. Pillar followed with his hit off Jason Foley (2-2). Ben Joyce (1-0), the last of four Los Angeles relievers who each tossed a scoreless inning, pitched the 10th to earn the victory.

Jake Rogers drove in three runs for the Tigers, two coming on his sixth homer of the season. Logan O'Hoppe clubbed his 12th for the Angels.

White Sox 11, Rockies 3

Paul DeJong finished 2-for-4 with a home run and three RBIs to lead Chicago past visiting Colorado.

DeJong's homer was one of four for the White Sox, joining Lenyn Sosa, Luis Robert Jr. and Korey Lee. Chicago scored 11 unanswered runs after trailing 3-0 and won a third straight game for just the third time this season.

Brendan Rodgers tallied two hits for the Rockies, including a solo home run, as Colorado dropped its fifth straight.

Reds 9, Cardinals 4

Jonathan India set a franchise record by doubling in his seventh straight game as Cincinnati coasted past host St. Louis.

India doubled twice to extend his hitting streak to 11 games. He also ran his multiple-hit streak to eight games. India, Stuart Fairchild and Will Benson drove in two runs each as the Reds took a 2-1 lead in the four-game series.

Paul Goldschmidt homered for the Cardinals and Matt Carpenter went 2-for-4 with a run and an RBI.

Diamondbacks 3, Athletics 0

Zac Gallen returned from the injured list to throw six brilliant innings and Ketel Marte, Jake McCarthy and Lourdes Gurriel Jr. had run-scoring hits as Arizona blanked visiting Oakland.

Gallen (6-4) allowed one hit and struck out seven in his first outing since leaving his May 30 start at the New York Mets with a strained right hamstring. Marte went 3-for-4 for as the Diamondbacks finished with 12 hits. Gurriel, Walker and Eugenio Suarez chipped in two hits apiece as Arizona won for the second time in its last seven games.

Brent Rooker and Miguel Andujar both singled for the Athletics, who were shut out for the ninth time this season.

Blue Jays 9, Yankees 3

Vladimir Guerrero Jr. had six RBIs with a two-run homer, a three-run double and a single, and Toronto defeated visiting New York.

Former Yankee Isiah Kiner-Falefa had four hits and an RBI to extend his hit streak to 13 games and help Toronto take a 2-1 lead in the four-game series. Toronto catcher Alejandro Kirk was 2-for-4 with two RBIs and threw out two runners trying to steal.

Toronto right-hander Chris Bassitt (7-6) allowed one unearned run, six hits and two walks with eight strikeouts in six innings. Austin Wells hit a two-run homer for New York.

Marlins 3, Phillies 2

Nick Gordon homered early and Jazz Chisholm Jr. delivered a tiebreaking RBI single in the seventh inning as Miami beat host Philadelphia.

Miami trailed 2-1 before scoring two runs with two outs in the seventh. Phillies starter Aaron Nola (9-4) was lifted after Miami tied it on back-to-back doubles by Otto Lopez and Nick Fortes. Chisholm then greeted Matt Strahm with a go-head run-scoring single.

Marlins reliever Andrew Nardi (1-0) tossed 1 1/3 scoreless innings of relief and Tanner Scott pitched a 1-2-3 ninth for his 12th save. Garrett Stubbs homered and Nola struck out nine while allowing three runs on six hits with zero walks over 6 2/3 innings.

Guardians 7, Royals 2

Cleveland got a boost from a controversial call, then took advantage of its momentum to rebound for a win over host Kansas City.

After losing the first two games of the series and trailing 2-1 in the fourth, Jhonkensy Noel pulled Cole Ragans' slider to left for a two-run homer, his second. Noel's high drive appeared to go foul, but after a crew chief review, the call was allowed to stand for a 3-2 Guardians lead.

Jose Ramirez had an RBI double and hit his 23rd homer, backing Tanner Bibee (7-2), who allowed two runs over six innings. Kansas City's Vinny Pasquantino collected two hits, including his 10th home run.

Cubs 5, Brewers 3

Ian Happ hit a tiebreaking two-run home run in the eighth inning to propel visiting Chicago past Milwaukee.

Michael Busch also hit a two-run homer and Pete Crow-Armstrong delivered an RBI for the Cubs, who evened the three-game series after losing 4-2 on Friday night. Luke Little (3-1) earned the win after escaping a seventh-inning jam.

Hector Neris secured his 11th save after striking out two with runners on first and second. Happ delivered the winning blast off Brewers right-hander Joel Payamps (1-4). Milwaukee got two hits and an RBI from both Brice Turang and William Contreras.

Orioles 6, Rangers 5

Heston Kjerstad hit a grand slam in the fifth inning, Anthony Santander also homered, and Baltimore won its fourth straight game by edging visiting Texas.

Santander added an RBI double, and Orioles starter Cade Povich (1-1), who made his major league debut on June 6, allowed two runs on five hits with three strikeouts and no walks in five innings for his first big-league victory. Closer Craig Kimbrel walked two batters in the ninth inning but recorded his 19th save.

Corey Seager, Derek Hill, Nathaniel Lowe and Adolis Garcia homered for the Rangers, who dropped their sixth straight game and took their 11th loss in 15 games. Rangers starter Michael Lorenzen (4-4) lasted five innings and was charged with five runs on four hits and four walks with three strikeouts.

Astros 9, Mets 6

Alex Bregman's two-out, two-run single in the eighth inning put visiting Houston ahead for good after rallying from a 6-1 deficit to end New York's four-game win streak.

Mauricio Dubon added insurance in the ninth with a two-out, two-run double down the left-field line. Seth Martinez (3-2) worked a clean seventh for the win and Josh Hader got his 12th save with a 1-2-3 ninth.

Pete Alonso laced a two-run single to cap a five-run second inning for the Mets, who got a solo home run from Mark Vientos an inning later to take a five-run lead. New York relievers Jake Diekman and Reed Garrett (7-3) combined to issue four walks during the Astros' three-run eighth, which slid Houston ahead 7-6.

Nationals 8, Rays 1

CJ Abrams hit a leadoff home run, then Washington posted a six-run seventh inning and broke a four-game losing streak with a rout of Tampa Bay in St. Petersburg, Fla.

Before leaving after seven innings, Abrams went 2-for-3 with his 13th home run, a double and a walk. He tallied two runs and two RBIs. Luis Garcia Jr. went 3-for-4 with a double, walk, two runs and an RBI. Harold Ramirez had two hits, including a triple, and two RBIs. Keibert Ruiz had two hits and an RBI.

Jake Irvin (6-6) was masterful over a six-inning start that took 96 pitches. The right-hander allowed just one hit, a homer to Brandon Lowe, while striking out five and walking three.

Braves 2, Pirates 1 (10 innings)

Adam Duvall lined a single into the gap in right-center leading off the bottom of the 10th inning to drive in designated runner Luke Williams from second base and give Atlanta a victory over visiting Pittsburgh.

After making a highlight-reel leaping catch at the right field wall to rob Michael A. Taylor of an RBI extra-base hit in the sixth, Duvall drilled an 0-1 fastball by Pirates reliever Kyle Nicolas (0-2) for his sixth career walk-off hit. Jarred Kelenic went 2-for-3 with a home run and a walk for Atlanta. Max Fried allowed just one run on six singles and walked three while striking out four.

Ke'Bryan Hayes had two hits and Bryan Reynolds extended his major-league-best hitting streak to 25 games with a ninth-inning triple for Pittsburgh. Pirates rookie Paul Skenes went six innings, giving up one run on six hits and walking two while striking out nine, including the final four batters he faced.

Twins 5, Mariners 1

Byron Buxton homered, doubled and drove in four runs as Minnesota defeated host Seattle.

Buxton's three-run shot off reliever Trent Thornton in the sixth inning gave the Twins homers in 18 consecutive games, matching a franchise record. Mitch Haniger went deep for the Mariners, who lost for just the second time in 11 home games this month.

Twins right-hander Pablo Lopez (8-6) pitched six innings for the victory, allowing one run on four hits, with one walk and nine strikeouts. Mariners starter Bryce Miller (6-7) took the loss despite allowing just two runs on five hits over five innings.