Steven Kwan and Jose Ramirez drove in two runs apiece in Cleveland's five-run second inning as the Guardians drubbed the host Tampa Bay Rays 7-1 on Friday night.

Ramirez went 3-for-5 with a double and a run, while Kwan finished 2-for-4 with two runs, two stolen bases and a walk. Austin Hedges homered and Nolan Jones had two hits for the Guardians.

Cleveland starter Gavin Williams (10-5) reached double figures in victories by scattering seven hits and yielding one run in seven innings. He whiffed three and walked three.

In reaching .500 (70-70), the Guardians posted 12 hits and won for just the sixth time in the past 16 games.

Junior Caminero hit a long solo homer and Josh Lowe and Yandy Diaz each had two hits for Tampa Bay (71-70), which had its season-best, seven-game winning streak end.

After failing to retire any of the three batters he faced in the Rays' 6-5 win over the Seattle Mariners on Tuesday, Griffin Jax opened and worked around two singles in a scoreless first.

Tampa Bay's Ian Seymour (3-1) was dealt his first career defeat after allowing five runs (one earned) and five hits in four innings following Jax. He fanned five and walked two.

In the second inning, the visitors grabbed their first lead of the series after Gabriel Arias bunted and reached on a fielding error by Seymour. Kwan ripped a two-run single four batters later, and Ramirez's double doubled the lead to 4-0. David Fry's RBI single rounded out the five-run frame.

Tampa Bay produced one hit in each of the first five innings but could not plate a baserunner against Williams.

Facing Rays reliever Brian Van Belle in the sixth, Hedges lifted a towering homer to left, his fifth. The solo shot made it 6-0. Pinch hitter George Valera recorded his first career RBI with a single later in the inning.

Caminero spoiled the shutout in the bottom of the sixth by clubbing a 421-foot rocket for his 41st homer and 103rd RBI.