Cristopher Sanchez extended his franchise-record scoreless streak to 50 2/3 innings before finally allowing a run, and the Philadelphia Phillies hit a pair of late homers to squeak out a 3-2 win over the visiting San Diego Padres on Wednesday.

Sanchez (7-2) did not allow a run in May and found out earlier Wednesday that he was named the National League's Pitcher of the Month. He was just as sharp in his first June outing, putting up zeros until Jackson Merrill hit an RBI single with two outs in the seventh.

In all, the Dominican left-hander yielded one run and four hits in seven frames, walking one and striking out eight. His scoreless streak is the fifth-longest in major league history and the longest ever by a left-handed pitcher.

J.T. Realmuto and Kyle Schwarber homered off Padres reliever Jason Adam (2-1) in the seventh. The Phillies' Jhoan Duran slammed the door in the ninth for his 14th save.

Dodgers 7, Diamondbacks 0

Shohei Ohtani pitched six strong innings for his fourth straight victory and reached base five times at the plate as Los Angeles blanked Arizona in Phoenix.

Ohtani (6-2) gave up two hits, walked one and struck out six while dropping his ERA to 0.74. He has pitched 61 innings, one short of the number needed to qualify for the major league leaderboard. If he qualified, he would easily be the ERA leader.

Kyle Tucker (three hits) belted a two-run homer in the second inning off Zac Gallen (3-5), and Freddie Freeman singled home two in a three-run third for a quick 5-0 lead. Ohtani had three singles and drew two walks to extend his on-base streak to 19 games, during which he is hitting .438 with four homers, 17 RBIs and 11 multi-hit games.

Tigers 7, Rays 2

Detroit's Dillon Dingler drove in four runs as the Tigers completed a sweep of Tampa Bay by scoring six times in the first four innings, easing away from the American League East leaders in St. Petersburg, Fla.

Dingler went 2-for-4 and was hit by a pitch. His fourth-inning homer was his third of the series and one of 10 Detroit deep shots in the sweep. Gleyber Torres was 3-for-5 with a double and three runs. Jake Rogers had two hits, including a solo homer. Kevin McGonigle managed a double, a single and a run. In his third start, Troy Melton (2-0) was sharp and yielded two runs on just four hits in eight innings.

Cedric Mullins had a solo homer and Yandy Diaz singled in a run, but the Rays produced just four hits -- none after the second inning -- and fell to 2-8 in their past 10. Nick Martinez (5-2), who had allowed two runs or fewer in his first 11 starts, was battered for six runs on nine hits in four innings.

Guardians 5, Yankees 4

Jose Ramirez homered in the sixth inning off Gerrit Cole as part of a three-hit performance as visiting Cleveland recorded a victory over New York.

After hitting doubles in three straight at-bats in Tuesday's 9-4 victory, Ramirez grounded out in his first at-bat before hitting a single in the fourth and a homer off Cole (1-1). Kyle Manzardo homered for the second straight night, while Rhys Hoskins hit a two-run homer in the fourth. Cleveland starter Gavin Williams (9-3) allowed three runs on four hits in 5 1/3 innings.

Jazz Chisholm Jr. hit a tying homer in the second and Jose Caballero homered in the fourth to make it a one-run contest. Following a pair of scoreless outings in his return from reconstructive elbow surgery that cost him 2025, Cole allowed four runs on six hits in 5 1/3 innings.

Giants 1, Brewers 0

Logan Webb took a no-hit bid into the seventh inning and Victor Bericoto hit his first career home run as San Francisco held on for a victory over Milwaukee.

Brice Turang recorded Milwaukee's first hit with one out in the seventh, an opposite-field single to left. The Brewers stranded the potential tying run at third in the ninth following a leadoff double by Christian Yelich. Keaton Winn retired the next three for his first save of the season.

Webb (3-4) gave up just the one hit in seven innings. He struck out four and walked one while throwing 95 pitches. The 29-year-old right-hander continued his dominance of the Brewers, improving to 5-0 with a 1.79 ERA in eight career starts.

Astros 11, Pirates 9

Cam Smith lined a tiebreaking two-run triple down the first base line, capping a six-run eighth inning as host Houston rallied for a win over Pittsburgh.

Isaac Paredes' two-run home run in the seventh shaved Houston's five-run deficit to 8-5. After Pittsburgh added a run in the eighth, the Astros erupted for six runs with two outs in the bottom of the frame, completing it against closer Gregory Soto (4-1). Astros closer Josh Hader made his season debut in the ninth and notched his first save. He had been sidelined due to biceps tendinitis.

Henry Davis hit his first career grand slam for the Pirates, while Nick Gonzales also went deep and drove in three. The anticipated pitchers' duel between Pittsburgh's Paul Skenes and Houston's Spencer Arrighetti fizzled as they combined to allow seven runs. Smith drove in three and Isaac Paredes homered and drove in three for the Astros.

Mets 7, Mariners 1

Bo Bichette went 4-for-4 with three RBIs and Freddy Peralta pitched six quality innings as New York snapped host Seattle's eight-game winning streak and salvaged the finale of a three-game interleague series.

Peralta (4-4), allowed one run on six hits. The veteran right-hander walked two and struck out six. A.J. Ewing had three hits and a run, Luis Torrens was 2-for-4 with two runs and Jared Young added two hits and an RBI.

J.P. Crawford went 3-for-4 with a double and homer for the American League West-leading Mariners. Starter George Kirby (5-5) gave up five runs (four earned) on nine hits over four innings, with one walk and five strikeouts.

White Sox 8, Twins 0

Rookie Sam Antonacci had an RBI double to highlight his career-high four-hit performance, helping Chicago coast past Minnesota in Minneapolis.

Antonacci added another double to lead off the eighth inning before coming around to score on Miguel Vargas' RBI single. Andrew Benintendi belted a two-run homer later in the inning to cap the scoring. Rookie Jacob Gonzalez recorded the first two RBIs of his career, as his two-run single highlighted his team's four-run first inning. Erick Fedde (1-5) scattered two hits over five scoreless innings.

Taj Bradley (5-2) permitted four runs on seven hits with five walks in 4 2/3 innings for the Twins to sustain his first loss since April 24.

Marlins 4, Nationals 1

Max Meyer allowed just one run on two hits over seven innings for visiting Miami, which beat Washington to complete the three-game sweep.

Joe Mack's two-out, two-run single off reliever Clayton Beeter (1-1) in the eighth put the Marlins ahead. Meyer (6-0) who struck out seven, won for the fourth time in his last five starts. Esteury Ruiz hit his third homer of the season in the second, a solo shot.

Washington starter Andrew Alvarez went 4 2/3 innings. The left-hander gave up four hits, including Ruiz's homer, and a walk. He also struck out five.

Red Sox 8, Orioles 1

Wilyer Abreu had Boston's first three RBIs before the Red Sox rattled off a five-run fifth inning en route to a win over visiting Baltimore.

Payton Tolle (3-2) pitched six scoreless innings for the Red Sox, who pounded out 15 hits and have won three of their past four games. Ryan Watson handled the final three innings for his first major league save. Ceddanne Rafaela and Willson Contreras both had three-hit performances.

Chris Bassitt (4-4) lasted just three innings and allowed six hits and three runs for the Orioles, whose three-game winning streak ended.

Royals 5, Reds 2

Michael Massey lined a go-ahead RBI single in the top of the ninth before Nick Loftin tacked on with a two-run homer, helping visiting Kansas City earn a victory over Cincinnati.

Vinnie Pasquantino also homered, while Stephen Kolek threw seven innings, allowing two runs on six hits, striking out eight and walking two for Kansas City, which clinched its first road series win since sweeping the Seattle Mariners from May 1-3.

After being scratched Monday with an illness, Chase Burns threw six innings of two-run, four-hit ball, striking out nine and walking one for the Reds, who dropped their fifth game in seven tries. Blake Dunn provided Cincinnati's runs with a two-run homer.

Braves 7, Blue Jays 3

Atlanta got a pair of three-run homers from Mauricio Dubon and Ozzie Albies and rolled to a win, handing Toronto its fourth straight loss.

Dubon went deep in the third against starter Patrick Corbin, while Albies homered in the seventh against Adam Macko. Grant Holmes (4-2) shook off a shaky start and allowed two runs on five hits and two walks. Holmes struck out four, including Brandon Valenzuela with runners on the corners to end a threat in the fourth.

Corbin (2-2) pitched five innings and allowed four runs on six hits and two walks, striking out one. It was the most runs he has allowed since his season debut April 10, as he absorbed his 12th straight loss to the Braves, a streak dating to Sept. 6, 2019. Valenzuela and Nathan Lukes hit solo shots for Toronto.

Athletics 5, Cubs 4 (10 innings)

Nick Kurtz singled home the go-ahead run in the top of the 10th, Justin Sterner threw a 1-2-3 bottom of the inning for his first career save and the Athletics overcame Chicago for a road victory.

After scoring twice in the eighth to draw even, the A's got automatic baserunner Alika Williams to third base in the 10th on a Jonah Heim infield out before Kurtz went the opposite way against Cubs reliever Ethan Roberts (0-1) to deliver his run-producing hit to left field. Hogan Harris (3-0) pitched a scoreless bottom of the ninth.

Cubs starter Colin Rea left with a 4-2 lead in the sixth, having allowed single runs in each of the first two innings. He limited the A's to four hits in his 5 1/3 innings. Seiya Suzuki hit a solo shot and Pete Crow-Armstrong added a two-run homer.

Cardinals 5, Rangers 3

Alec Burleson drove in three runs with a two-run double and an RBI single as St. Louis beat visiting Texas to avoid a series sweep.

Cardinals starter Andre Pallante (6-4) gave up one run on three hits over 5 2/3 innings. Riley O'Brien worked around a leadoff walk in the ninth for his 15th save. St. Louis' Jordan Walker went 3-for-4 with three runs.

Joc Pederson had a two-run triple for the Rangers, whose five-game winning streak ended. MacKenzie Gore (4-5) allowed four runs on nine hits over 4 2/3 innings.

Angels 11, Rockies 4

Nick Madrigal and Wade Meckler had four hits apiece as Los Angeles salvaged the finale of a three-game series against Colorado in Anaheim, Calif.

Los Angeles' Vaughn Grissom homered and drove in three runs. Madrigal had an RBI and a run, and Meckler doubled and scored twice. Oswald Peraza went 2-for-5 with a double, two RBIs and a run, and Jose Siri hit an RBI double and scored two runs for the Angels, who tied a season high with 16 hits. Angels starter Walbert Urena (3-4) allowed three runs on three hits over six innings.

Tyler Freeman homered, Troy Johnston had two hits and two RBIs and Hunter Goodman doubled, walked, stole a base and drove in a run for Colorado, which had won four of its previous five games. Rockies starter Michael Lorenzen (2-8) permitted eight runs on 10 hits in 3 1/3 innings.