Seattle slugged four solo home runs and Bryan Woo pitched seven scoreless innings as the host Mariners downed the Arizona Diamondbacks 5-1 on Saturday for their fifth consecutive victory.

Julio Rodriguez, Luke Raley, Dominic Canzone and Colt Emerson went deep as the Mariners moved above .500 (30-29) for the first time since they were 3-2 on March 30.

Woo (5-3) retired the first 13 batters he faced before Adrian Del Castillo lined a one-out single to center field in the fifth. An out later, Ildemaro Vargas lined a single to center, but Woo caught Jose Fernandez looking at a called third strike to get out of the inning. Those were the only two hits Woo allowed. The right-hander didn't walk a batter and struck out nine, matching his season high.

Diamondbacks starter Ryne Nelson (2-4) gave up five runs (four earned) on seven hits over 5 1/3 innings. The right-hander didn't walk a batter and struck out three as Arizona lost its second straight game.

Braves 5, Reds 2

Ronald Acuna Jr. launched a pair of home runs to help Atlanta down host Cincinnati and take the first two games of the three-game weekend series.

Acuna tallied his first multi-homer game of the year, hitting his third and fourth home runs in the last three games after he had just two in his first 42 games. Jorge Mateo and Matt Olson each added a solo homer for the Braves, who won their fourth game in five tries and became the first team in the majors to reach 40 wins.

Martin Perez (3-3) allowed two runs on four hits over five innings, striking out a pair and walking three. Raisel Iglesias completed his 10th save in as many tries with a perfect ninth inning. Brady Singer (2-5) yielded three runs on four hits in five innings, walking four and striking out two as the Reds dropped their third straight and fell to 9-17 in May.

White Sox 7, Tigers 1

Edgar Quero, Colson Montgomery and Andrew Benintendi hit home runs as host Chicago defeated struggling Detroit.

White Sox starter Anthony Kay gave up one run and six hits in five innings. Chicago goes for the three-game sweep Sunday. The Tigers have lost three straight and are just 6-21 in May.

Detroit's Framber Valdez gave up four runs and six hits in 6 2/3 innings. The southpaw struck out four and walked two in 89 pitches. Wenceel Perez homered for the Tigers.

Orioles 6, Blue Jays 5

Pete Alonso capped host Baltimore's five-run ninth inning with a walk-off single to stun Toronto and end a two-game skid.

The Orioles, who drew 11 walks in the game, rallied with four hits, three walks and a hit batter in the ninth after being held to three singles through eight innings. Albert Suarez (2-0) pitched the ninth and allowed one run but earned the victory.

The Blue Jays' Kazuma Okamoto doubled in two runs in the eighth, but Toronto's winning streak was halted at four games. Vladimir Guerrero Jr. racked up four hits, including a double, and scored twice, while Ernie Clement had two singles as part of the Blue Jays' 11-hit attack. Jeff Hoffman (4-4) gave up ninth-inning runs on Leody Taveras' triple, Baltimore's first extra-base hit of the game, and Jackson Holliday's single.

Rangers 7, Royals 6

Ezequiel Duran dropped a walk-off, RBI single into right field, and Texas rallied for three runs in the ninth inning to win over scuffling Kansas City in Arlington, Texas.

The Rangers trailed 6-4 entering the ninth, when Joc Pederson led off with an opposite-field homer to right off Lucas Erceg (3-3). Josh Jung and Brandon Nimmo followed with back-to-back infield singles and Jake Burger's third hit tied the contest. Duran came through with a ball that fell in front of right fielder Jac Caglianone, allowing Nimmo to score.

The Royals, who have lost five straight, managed just three hits and could not take advantage of three walks allowed by Texas' Kumar Rocker, who had a 3-0 lead when he left following the sixth inning. However, Kansas City finally broke through in the seventh and eventually built a 6-3 lead in the eighth.

Pirates 10, Twins 9

Jake Mangum and Nick Gonzales each totaled three hits and two RBIs to lead host Pittsburgh to a wild win over Minnesota.

Mangum's second-inning solo home run off Twins starter Bailey Ober (6-3) was his first as a Pirate, and ignited a six-run second inning that gave Pittsburgh a 7-1 lead. Ober allowed three home runs in the first two innings, including a three-run homer to Oneil Cruz in the second and a leadoff solo homer to Spencer Horwitz in the first.

Minnesota answered in the third on a Kody Clemens RBI triple, and produced five runs in the fourth off Pirates starter Mitch Keller to tie the game at 7. Mangum's RBI single in the fifth then put the Pirates ahead for good. After starter Mitch Keller lasted just four innings, Yohan Ramirez (3-2) pitched the first of four scoreless innings by Pirates relievers to get the win.

Astros 9, Brewers 2

Jeremy Pena and Isaac Paredes capped three-run uprisings with two-run, extra-base hits to help Houston down visiting Milwaukee.

Pena finished 3-for-5 with a home run and two RBIs while Paredes went 1-for-3 with a double and a walk. Yordan Alvarez and Jake Meyers also produced multi-hit games for the Astros, while Christian Walker clubbed a three-run shot in the eighth.

Brewers right-hander Brandon Sproat (1-4) retired seven of the next eight batters after the Pena homer, but the right-hander came undone when Pena led off the fifth with a single. He was lifted after two more batters but was charged with two of the three runs that scored.

Red Sox 9, Guardians 1

Jarren Duran had a three-run homer and Connor Wong singled home a pair in a six-run ninth inning, lifting visiting Boston to a victory over Cleveland.

Wong gave the Red Sox a 2-1 lead in the sixth with an RBI double off Matt Festa (1-1), scoring pinch hitter Marcelo Mayer, and tacked on two more in the ninth against Will Dion. Boston won for the second time in its last eight games, buoyed by a strong start from Sonny Gray (6-1), who secured his fourth May win by allowing one run on four hits over six innings.

Jose Ramirez had a first-inning RBI double for the Guardians, who scored their only run two batters into their half of the first. Starter Parker Messick didn't factor into the decision but was again effective, giving up one run on five hits over five innings.

Angels 14, Rays 3

Rookie Wade Meckler slugged his first career grand slam in the opening inning, and Los Angeles evened its series with Tampa Bay by pummeling the Rays in St. Petersburg, Fla.

Meckler went 2-for-4 with two runs and a stolen base and staked his club to a 4-0 lead before the Rays batted as the Angels breezed to their sixth win in eight games. Mike Trout was 2-for-3 with a homer, three runs and two walks. Jo Adell ripped a three-run homer and Oswald Peraza also went deep. Reid Detmers (2-5) allowed three runs on five hits in five innings.

Yandy Diaz homered in his two hits and scored twice, and Junior Caminero had two doubles, two walks and an RBI for Tampa Bay. Drew Rasmussen (4-2) surrendered a season-high five runs on four hits to lose for the first time in five May starts.

Cubs 6, Cardinals 1

Pete Crow-Armstrong busted out of his slump with a season-high four hits to lead Chicago to a victory over host St. Louis.

The Cubs center fielder entered with a modest four-game hitting streak, but he was hitting just .154 (10-for-65) in his last 19 games. His 4-for-5 night included a double and his seventh home run of the season. He scored twice and drove in a pair. Ben Brown (2-2) limited the Cardinals to just three hits and a run over seven innings, which tied his career high.

St. Louis struck first in the fourth with Alec Burleson's one-out single to right scoring JJ Wetherholt, who led off the inning with a single up the middle. Starter Kyle Leahy scattered six hits in 4 1/3 innings for the Cardinals.

Rockies 8, Giants 3

Jake McCarthy homered, singled twice and drove in four runs, Ryan Feltner returned to the rotation with six shutout innings and Colorado beat San Francisco in Denver.

Kyle Karros also went deep, and TJ Rumfield and Willi Castro had two hits each for Colorado, which has won consecutive games for the first time since May 7-8. Drew Gilbert homered among his two hits, and Jung Hoo Lee and Matt Chapman also had two hits for the Giants, who have lost five in a row.

Feltner (2-1) was activated from the injured list (right ulnar nerve inflammation) to make his first start since April 23. The right-hander retired the first five batters he faced before Chapman's two-out double in the second, and he erased leadoff singles in the third and fifth innings with double-play grounders.

Nationals 9, Padres 4

Luis Garcia Jr. hit a two-run single to highlight a six-run seventh inning as host Washington rallied past San Diego.

Garcia had two hits and Drew Millas homered for the Nationals, who had lost two straight.

Xander Bogaerts, Manny Machado and Fernando Tatis Jr. homered for the Padres, who have lost five of their past six games.

Mets 6, Marlins 1

Christian Scott pitched five effective innings for his first career win, and New York supported him with three runs in the fourth inning of their victory over visiting Miami.

Mark Vientos hit a two-run double and Marcus Semien hit an RBI single in the fourth, when the Mets went ahead 3-0 against the Marlins' Tyler Phillips (0-1). Scott (1-0) allowed one run on five hits to lift New York to its second straight win over Miami after getting swept in a three-game series in Florida last weekend.

Liam Hicks delivered an RBI single in the fifth for the Marlins, who dropped their fourth straight and lost for the seventh time in 11 games. Miami also set a season high by striking out 15 times.

Athletics 6, Yankees 4

Shea Langeliers and Nick Kurtz drilled two-run homers and Tyler Soderstrom hit a solo shot as the Athletics beat visiting New York at West Sacramento, Calif.

J.T. Ginn (3-3) pitched six solid innings, yielding just one unearned run and four hits as the Athletics snapped a four-game losing streak. Kurtz went 3-for-4 and scored twice and Soderstrom reached four times on three hits and one walk.

The Yankees had just six hits -- none producing a run -- while seeing a five-game winning streak come to an end. New York's Ryan Weathers (2-3) served up three homers and allowed five runs and six hits over 6 2/3 innings. The left-hander matched a season-best with 10 strikeouts and walked three.

Phillies 4, Dodgers 3

Edmundo Sosa hit a go-ahead two-run home run with two outs in the eighth inning as Philadelphia rallied past Los Angeles to improve to 4-1 on a six-game West Coast road trip.

Bryce Harper added an RBI single in a three-run eighth, while Alec Bohm hit a second-inning home run for the Phillies. Orion Kerkering (3-0) gave up a run in the seventh and Jhoan Duran pitched the ninth for his 12th save.

Alex Call had an RBI single and a run scored for the Dodgers, who saw their season-best six-game winning streak snapped. Left-hander Tanner Scott (1-2) gave up all three Philadelphia runs in the eighth inning.