The Pittsburgh Pirates got a home run from Spencer Horwitz as they emphatically snapped their four-game losing streak with a 7-0 win over the host St. Louis Cardinals on Wednesday night.

Carmen Mlodzinski (4-3) threw five scoreless innings for Pittsburgh, which outhit the Cardinals 15-5. Four relievers completed the shutout. Pirates rookie Konnor Griffin went 4-for-5 with three runs.

There was also a milestone moment for Pirates center fielder Jhostynxon Garcia, who recorded his first career RBI in the win. Garcia was making only his second start for Pittsburgh after being called up on Tuesday.

JJ Wetherholt went 2-for-4 at the top of the order for St. Louis, which had won four of its previous five games.

Mlodzinski worked around a single and a walk to strand two on base in the first inning. The Pirates struck first in the top of the second with Horwitz's fourth home run of the season.

Pittsburgh mounted a two-out rally in the fourth to extend its lead. After Griffin reached on his first of two infield singles and Endy Rodriguez walked, Garcia's RBI single doubled the Pirates' advantage.

Cardinals starter Michael McGreevy (3-3) was chased after loading the bases without recording an out on three consecutive singles in the sixth. Justin Bruihl came on in relief and got out of the jam, but not without allowing Pittsburgh to add on with Nick Gonzales' sacrifice fly.

McGreevy was charged with three runs in five-plus innings. The right-hander struggled to miss bats, allowing 10 hits and striking out only one hitter while walking one.

St. Louis also loaded the bases in the bottom of the sixth, but Yohan Ramirez struck out Masyn Winn, and Jake Mangum made a sliding grab at the wall in right to rob Cesar Prieto of extra bases and keep the shutout intact.

The result was put beyond doubt when Pittsburgh put up four runs off Matt Svanson in the eighth. Mangum and Gonzales hit RBI singles before Bryan Reynolds capped the rally with a two-run double.