Milwaukee Brewers first baseman Andrew Vaughn (hand) is battling a hand injury, per Adam McCalvy of MLB.com. McCalvy reports that Vaughn's injury is prompting Milwaukee to promote catching prospect Jefferson Quero to provide the team the flexibility to use normal backup catcher Gary Sanchez at first base. Vaughn appears likely to be placed on the injured list, but it's not entirely clear how much time Milwaukee expects him to miss. The 27-year-old started Milwaukee's opener on Thursday against the Chicago White Sox at first base and batted cleanup. Vaughn closed the 2025 season on a tear, hitting .308/.375/.493 with nine home runs, 46 RBI, and 26 runs scored across 254 plate appearances with Milwaukee. If he's forced to miss time, Sanchez and left-handed hitting outfielder/first baseman Jake Bauers could be the leading candidates to cover first base for the Brewers.

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Los Angeles Dodgers closer Edwin Diaz converted his first save chance with his new team on Friday night in the Dodgers' 5-4 win over the Arizona Diamondbacks. Diaz allowed a walk but struck out two without allowing a hit in a scoreless ninth inning. The 32-year-old signed a three-year, $69 million contract with Los Angeles this past winter after a six-season run with the New York Mets. Across 66 1/3 innings with New York in 2025, Diaz recorded a 1.63 ERA and a 0.87 WHIP with 98 strikeouts, six wins, and 28 saves. He's recorded a strikeout rate of at least 38% in six out of the last seven seasons where he's pitched. When healthy, Diaz is arguably the best closer in baseball and should get plenty of save chances while pitching for the Dodgers in 2026.

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Pittsburgh Pirates outfielder Oneil Cruz is not in the starting lineup for his team's matchup with the New York Mets and left-handed starting pitcher David Peterson on Saturday. Switch-hitter Jake Mangum will take Cruz's spot in center field and bat ninth. Cruz's 2026 season got off to a rough start in Pittsburgh's opener against the Mets on Thursday, as he struck out three times in five plate appearances and misplayed a ball in center field that led to multiple runs for New York. The 27-year-old owns a slash line of .172/.247/.313 with a 38.4% strikeout rate in 401 career plate appearances against left-handed pitching. It appears that Pittsburgh is planning to deploy Cruz in a true big-side platoon role in center field, at least to begin 2026. Cruz's power/speed profile makes him a high-upside fantasy outfielder, but his ability to rack up counting stats is limited by his lack of everyday playing time.

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Toronto Blue Jays third baseman Kazuma Okamoto has been moved up to the cleanup spot in his team's lineup for Toronto's matchup on Saturday against the Athletics and left-handed starting pitcher Jeffrey Springs. Okamoto batted seventh for the Blue Jays' opener on Friday with the A's throwing right-handed starting pitcher Luis Severino. Okamoto performed well in his MLB debut, going two-for-three with a walk and two runs scored. The 29-year-old is expected to play a key role as the Blue Jays' everyday third baseman in 2026 after the team brought him over from Japan on a four-year, $60 million contract. Okamoto's prominent spot in the lineup against left-handers should help him rack up counting stats for fantasy managers, and could be an indicator of his potential to move up in the lineup against righties if he proves he can handle MLB pitching.

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Texas Rangers ace Jacob deGrom (neck) has been scratched from his scheduled start on Saturday against the Philadelphia Phillies due to neck stiffness. Left-hander Jacob Latz will make the start in deGrom's place. After failing to reach 100 innings pitched in four consecutive seasons from 2021 through 2024 due to multiple different arm injuries, deGrom finally put together a healthy campaign in 2025. Across 172 2/3 innings (30 starts), the 37-year-old recorded a 12-8 record with a 2.97 ERA, 0.92 WHIP, and 185 strikeouts. On the bright side, deGrom's current issue is not arm-related, and he may simply need to be pushed back a few days before he can make his first start of 2026. However, any injury issue for deGrom is a concern for fantasy managers, given his extensive track record of missed time in recent years. Texas wraps up its series with the Phillies on Sunday before heading to Baltimore for a three-game set with the Orioles that begins on Monday evening.

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Washington Nationals shortstop CJ Abrams is currently away from the team due to the passing of a family member, per Mark Zuckerman of Nats Journal. Nationals infielder Nasim Nunez will fill in for Abrams at shortstop for the team's game on Saturday against the Chicago Cubs, with infielder Jorbit Vivas taking Nunez's regular spot at second base. Abrams went one-for-four with two RBI in Washington's Opening Day win on Thursday against the Cubs. It's not entirely clear how long Abrams will be away from the team, but it's unlikely to be an extended absence. The Nationals wrap up their series in Chicago on Sunday before traveling to Philadelphia for a three-game series that begins on Monday night.

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The Milwaukee Brewers are calling up catching prospect Jeferson Quero from Triple-A Nashville on Saturday, a source told Daniel Alvarez-Montes of ElExtra Base. Quero, the team's No. 8 prospect per MLB Pipeline, will give the Brewers more catching depth behind William Contreras and Gary Sanchez. The 23-year-old Venezuelan backstop will be making his big-league debut whenever he gets into a game, but right now, his path to playing time appears blocked in Milwaukee. Quero dealt with hamstring and shoulder injuries in the minors in 2025 and was limited to 250 plate appearances, hitting .255/.336/.412 with 11 home runs, 57 RBI, and 42 runs scored in 69 games on the farm. It's a questionable early-season call-up unless one of Contreras or Sanchez is currently dealing with an injury that we are unaware of. Quero is considered one of baseball's best defensive catching prospects, although he's not on MLB Pipeline's list of top-10 catching prospects overall.

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Miami Marlins right-handed closer Pete Fairbanks was successful in his first save opportunity on Opening Day on Friday, locking down the team's 2-1 victory over the visiting Colorado Rockies. In his inning of work, Fairbanks allowed a hit and struck out one batter to pick up his first win of the 2026 season with his new squad. The 32-year-old veteran signed a one-year, $13 million deal with the Fish over the winter to be their closer for this season, and if he can stay healthy, he'll have a good shot at his first career 30-save campaign in the big leagues. Fairbanks is in his eighth season in MLB and has 91 career saves with the Texas Rangers and Tampa Bay Rays. He had a 2.83 ERA, 1.04 WHIP, a career-high 27 saves, 59 strikeouts, and 18 walks in 60 1/3 innings in 2025 in his final year in Tampa. Despite being in Miami, Fairbanks should be a pretty stable fantasy closer, as he's had at least 20 saves in each of the last three seasons.

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Toronto Blue Jays infielder Andres Gimenez was the hero for the Blue Jays on Friday in their 3-2 Opening Day win over the visiting Athletics on Friday, driving home the winning run in the bottom of the ninth inning. Gimenez finished the game 2-for-3 with a two-run triple, an RBI single, and a walk out of the nine-hole. The 27-year-old, who is now playing shortstop for the Blue Jays with Bo Bichette no longer in town, has been riding high of late, also helping Team Venezuela win the World Baseball Classic this spring. Gimenez was an All-Star back in 2022 with the Cleveland Guardians and had 70 total stolen bases from 2022 to 2024, but he's still mostly useful to Toronto for his defensive prowess up the middle. He has a .254/.317/.383 career slash line in 670 career games, and has never reached the 20-home run mark. Offensive performances like Friday night will probably be few and far between for Gimenez, but his speed can be useful in deeper leagues.

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Cleveland Guardians outfield prospect Chase DeLauter is now up to three home runs on the year after just the first two games of the season after he homered again in the team's 5-1 loss to the Seattle Mariners on Friday night. DeLauter, batting in the two-hole for Cleveland, went 1-for-4 on the night with a solo home run and a strikeout. In his first two games of the 2026 season, the 24-year-old left-handed slugger has gone 4-for-9 with three home runs (all solo jobs). It's been nice to see from the former 16th overall pick in 2022 out of James Madison University in his first taste of major-league pitching. He also looked good at the plate this spring, batting .459/.535/.838 with a 1.373 OPS, three homers, five doubles, 10 RBI, 10 runs scored, six walks, and four strikeouts in 14 Cactus League games. Durability has been an issue for DeLauter in the minors, but for now, fantasy managers need to swoop him up where he's available, as he's looking like a potential early favorite for American League Rookie of the Year if he can stay on the field for Cleveland.

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St. Louis Cardinals catcher Ivan Herrera (knee) will bat second and play catcher for Saturday's contest against the Tampa Bay Rays. Herrera was the designated hitter for the Cardinals' regular-season opener on Thursday, but it appears that he's now healthy enough to get back into the defensive alignment. The 25-year-old is looking to build off a breakout 2025 campaign in which he slashed .284/.373/.464 with 19 home runs, 66 RBI, a 9.5% walk rate, an 18.6% strikeout rate, and 137 wRC+. He went 0-for-4 on Opening Day, but it's far too early to panic. He still has tremendous upside given his production at the plate and near-league-average defense. As it stands, he ranks #10 among catchers in RotoBaller's latest fantasy baseball rankings for 2026.

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Los Angeles Angels right-handed reliever Jordan Romano is emerging as the team's primary closer with all of Kirby Yates (knee), Ben Joyce (shoulder), and Robert Stephenson (elbow) on the injured list to begin the 2026 season. Romano picked up his first save of the year in Thursday's 3-0 Opening Day win over the Houston Astros, and although it wasn't a save situation, he pitched in the ninth inning for a second straight day in Friday's 6-2 victory. He had a clean inning of work to finish off the victory, striking out two batters. Romano had a rough couple of seasons the last few years, but he topped out at 95.7 mph on Friday and is looking more like the version of himself that had 36 saves in back-to-back years with the Toronto Blue Jays in 2022 and 2023. Veteran left-hander Drew Pomeranz could also see some save chances for the Halos early in the year with the back end of the bullpen banged up, but for now, Romano is the arm to roster for fantasy managers in need of saves.

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Houston Astros relief pitcher Bennett Sousa (oblique) has been diagnosed with a Grade 1 oblique strain, according to Chandler Rome of The Athletic. He was placed on the injured list but is not expected to miss more than the minimum 15 days. Sousa was a key part of the Astros' bullpen in 2025, posting a 2.72 FIP with 10.48 K/9, 2.66 BB/9, and 0.71 HR/9 over 50.2 innings of work. He also recorded four saves. Sousa didn't pitch in a 2026 regular-season game before landing on the IL, but he did throw three innings of one-run ball in spring training. Without consistent save opportunities, Sousa isn't on the fantasy radar. Still, Astros fans will patiently await his return to the bullpen, given how well he pitched last year.

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Miami Marlins first baseman Christopher Morel (oblique) has been placed on the injured list, according to Craig Mish of SportsGrid. In a corresponding move, first baseman Deyvison De Los Santos was recalled from Triple-A. Morel has yet to make his 2026 regular-season debut, as he was scratched from the Opening Day lineup on Friday with a left oblique strain. The 26-year-old is coming off a lackluster year with the Rays in which he slashed .219/.289/.396 with an 8.2% walk rate, a 35.7% strikeout rate, and 90 wRC+ across 105 games in the majors. While Morel primarily played left field last year, he's the Marlins' projected first baseman for 2026. De Los Santos and Liam Hicks should fill in at first base for the duration of his IL stint.

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Detroit Tigers starting pitcher Jackson Jobe (elbow) is expected to play catch from 120 feet on three different occasions this upcoming week, according to Evan Petzold of Detroit Free Press. The former No. 3 pick is making decent progress as he recovers from Tommy John surgery. He still has a long road ahead of him, though, as the Tigers previously said they hoped he could return in September. Jobe logged 10 starts before landing on the injured list last year. He had a 4.22 ERA, 5.18 FIP, 7.16 K/9, 4.96 BB/9, and 1.29 HR/9. This was a somewhat uninspiring stat line for the right-hander, given that he didn't rack up strikeouts, he struggled with walks, and he was unable to induce much weak contact (43.2% ground ball rate). Still, Jobe is an exciting arm with impressive velocity, so the Tigers would love to get him back just in time for the postseason.

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The Boston Red Sox have re-signed infielder Brendan Rodgers (shoulder) to a two-year minor league contract, according to Chris Hatfield of SoxProspects.com. Rodgers had been in camp with the Red Sox, but he was released this past week following shoulder surgery. Now, he's back in the organization on a new deal that will allow him to rehab in 2026 before returning as a healthy depth option in 2027. It's a low-risk move that could give the Red Sox a potential bench middle infielder next year. Rodgers hasn't been a productive hitter since 2024, which was his final year with the Rockies. However, he continues to offer a right-handed bat, veteran experience, solid glovework, and defensive versatility.

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The San Diego Padres have signed veteran relief pitcher Jose Leclerc to a minor league contract, according to Jon Heyman of The New York Post. The 32-year-old hasn't pitched since last April, when he suffered a shoulder injury that eventually required surgery. Presumably now fully healthy, Leclerc will offer bullpen depth in the minor leagues. His veteran experience and track record make him a strong candidate for a promotion to the majors at some point this season. Across nine innings before his injury last year, the right-hander allowed six earned runs with five walks, eight strikeouts, and three home runs. He fared better over a larger sample size in 2024 with the Rangers, pitching to a 3.66 xFIP with 12.02 K/9, 4.32 BB/9, and 0.95 HR/9.

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Los Angeles Dodgers starting pitcher Emmet Sheehan "had issues maintaining his stuff and command in spring," according to Fabian Ardaya of The Athletic. The right-hander saw his velocity and stuff get worse deeper into games, and the team reportedly attributed it to "some mechanical stuff he was working through." The struggle to maintain velocity and stuff didn't stop at the end of spring training, though. Rather, the issue persisted into Sheehan's 2026 regular-season debut against the Arizona Diamondbacks on Friday. His fastball averaged 95.5 mph in the first inning, but that number dropped below 94.0 mph in the second and third innings, and it fell to 92.8 mph in the fourth. Sheehan still struck out six batters over 3.1 innings of work, but he was also roughed up to the tune of four runs, five hits, and two walks. The Dodgers and the right-hander will now have to continue working on fixing the mechanical issue before his next scheduled start on Friday, April 3, against the Washington Nationals.

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According to Kevin Barral of Fish on First, the Miami Marlins are promoting first base prospect Deyvison De Los Santos to the major-league roster. De Los Santos began the 2026 campaign with Triple-A Jacksonville but needed just one game before earning his first call to the big leagues. On Friday night in Jacksonville's season opener, De Los Santos went 2-for-4 with a home run. Earlier on Friday, the Marlins scratched first baseman Christopher Morel (oblique) from the starting nine. Given that the Marlins promoted their top first base prospect, Morel could be in danger of missing time on the injured list. In 2025, De Los Santos spent nearly his entire season with Triple-A and held a .241/.311/.363 line with 11 doubles and 12 home runs. For now, he is worth adding in deeper 12+ team leagues as a speculative source for power at the corner infield spot.

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Los Angeles Angels future Hall of Fame outfielder Mike Trout was at it again in Game 2 of the regular season in Friday's 6-2 win on the road against the Houston Astros. Trout went 3-for-4 with a solo home run and a walk, and he's now 4-for-6 at the plate with two home runs, four walks, and a stolen base through the season's first two games. The 34-year-old has looked like vintage Mike Trout in the early going, but fantasy managers are probably cautiously optimistic after all the time he has missed in recent seasons due to injuries. The three-time MVP and 11-time All-Star has played over 100 games only twice in the last five seasons due to various injuries, which have also curbed his stolen-base numbers (14 steals since the start of 2021). Trout hit only .232 in 130 games in 2025, but he managed to club 26 home runs in 556 plate appearances. If he can stay healthy, Trout could end up being a steal for fantasy managers, especially if he runs more than he has in the last five years.

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