Pittsburgh Pirates left-handed reliever Gregory Soto (2-0) has been excellent so far in 2026, making 14 appearances on the season with a 1.98 ERA and 0.80 WHIP with 20 strikeouts in 13 2/3 innings pitched. Under the hood, he has also been dominant (1.86 xERA and .137 xBA). Currently, he is splitting closing duties with right-hander Dennis Santana, who earned 16 saves last season. Although Soto's stuff and stats project better than Santana's, Santana is still throwing the ball well, with a 0.69 ERA and 0.85 WHIP; however, regression may catch up with Santana at some point, as he has a 3.52 xERA and is missing fewer bats (25.3 percent whiff rate to Soto's 31.1 percent). While Soto holds standalone value as things are now, he appears to be the higher upside reliever to roster amongst the two Pirate backend relievers, making him a must-add reliever in deeper formats.

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Cleveland Guardians left-handed pitcher Joey Cantillo has been rock solid in 2026, posting a 3.26 ERA, 1.32 WHIP, and a 27.2 percent strikeout rate. Under the hood, he has been solid as well, with a 3.85 xERA and .226 xBA. The Guardians also know how to develop pitchers, and, pitching for an organization that typically squeezes the most out of its pitchers, Cantillo remains a good add in most 12- or more-team formats. Cantillo has made six starts on the season and has yet to allow more than three earned runs in any of those outings. While he does not work deep into games, having gone only six innings in one of those starts, he limits loud contact and big innings. Last season, in 95 1/3 innings over 13 games, he posted a 3.21 ERA and 1.26 WHIP. Now, through six starts this year, we have a 19-start sample size for Cantillo, in which he has been in the mid-threes ERA with a WHIP between 1.25 and 1.32, which is valuable to own in fantasy baseball. Next up for Cantillo is a start at the Athletics over the weekend.

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Los Angeles Dodgers left-hander Alex Vesia will have the chance to pick up some save opportunities for the Dodgers with Edwin Diaz (elbow) expected to miss around three months after he had surgery on his right elbow to remove loose bodies. Tanner Scott and Blake Treinen are also among the Dodgers relievers with a chance to close out games; however, Treinen has struggled, posting a 4.50 ERA and now has two blown saves on the season. Scott earned the save on April 23; however, Vesia is two-for-two on save opportunities after closing out two games on April 11 and April 14. Vesia has a 1.93 ERA and 0.86 WHIP in 9 1/3 innings pitched on the season, and although this may be a committee for the time being, Vesia has the opportunity to take over if he can outperform Scott and Treinen, and at the very least, split save opportunities while Diaz is out, making him fantasy relevant in deeper formats.

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Milwaukee Brewers left-hander Kyle Harrison put together arguably the best start of his MLB career on Sunday, going six innings, allowing only one hit, no earned runs, one walk, and punching out 12 batters. Harrison had 23 whiffs, 13 of which came on his four-seamer and fired in 71 percent of his pitches for strikes. The outing was a much-needed bounce-back effort for Harrison, as his start earlier in the week in Detroit was very inefficient and required 72 pitches over three innings. On the season, Harrison is now (2-1) with a 30:8 K:BB ratio, 2.28 ERA, and a 1.06 WHIP. His next start lines up over the weekend in Washington to take on the Nationals, where Harrison will be a popular streamer given his recent effort on Sunday. In 12-team formats, Harrison is a must-add off the waiver wire and should not be available given his recent performance and connection to the Brewers organization, which continuously squeezes out every ounce of talent from their pitchers.

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Dodgers left-hander Justin Wrobleski has been elite in his transition back to a starting role this season, posting a 1.50 ERA and 0.97 WHIP through five games. Wrobleski has continued his steady growth entering his third year with Los Angeles and is climbing quickly within an already loaded rotation. The 25-year-old owns a 0.69 ERA in April and has already earned four wins, showing the ability to work deep into games. Wrobleski has attacked the strike zone consistently while generating more weak contact. He made only two starts for the Dodgers last season, but he looks fully comfortable in this expanded role. If this level continues, Wrobleski will remain one of the best waiver wire additions for fantasy managers seeking pitching help.

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San Diego Padres right-hander Randy Vasquez has been dominant through five starts this season, posting a 1.88 ERA, 1.08 WHIP, and 30 strikeouts across 28.2 innings. Vasquez has allowed more than one run only once, showing impressive consistency in his third year with San Diego. The 27-year-old logged a 3.84 ERA in 28 games last season, but he appears ready to take another step in 2026. His swing-and-miss profile has improved dramatically, with his K% rising to 26.3 after finishing at 13.7 last year. If this growth continues into May, he could become a key fantasy waiver wire target and an important piece of the Padres rotation.

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The New York Yankees have called up outfielder Jasson Dominguez after a dominant start at Triple-A Scranton/Wilkes-Barre. Dominguez hit .306 with an .875 OPS and three home runs in 22 games, earning another opportunity with the first-place Yankees. The 23-year-old has flashed impact tools since debuting in 2023, but he has not yet delivered consistent production in the majors. Dominguez slashed .257/.331/.388 across 123 games last season and was left off the Opening Day roster this year. This promotion gives him a fresh chance to translate his minor league momentum into everyday value. If he starts quickly, Dominguez could secure a meaningful role in a potent Yankees lineup.

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Athletics right-hander Jack Perkins is quickly emerging as the club's preferred ninth-inning option after recording saves in each of his last two appearances. Perkins has been one of the early surprises in the Athletics bullpen, posting a 3.18 ERA and 1.15 WHIP through six outings. Scott Barlow entered the season as the likely favorite for save chances, but he blew his lone opportunity and has shifted into more of a setup role with five holds already. Perkins is in his second major league season and is showing the poise and stuff needed for high-leverage work. His recent usage suggests growing trust from the coaching staff as the Athletics sort out late-game roles. Fantasy managers searching for saves should act quickly, as Perkins is trending toward steady closing opportunities moving forward.

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Milwaukee's SP Kyle Harrison recorded 12 strikeouts in 6 innings collecting the win in a 5-0 win over the Pirates on Sunday, Apr. 26.

New York Yankees right-hander Luis Gil has been optioned to Triple-A Scranton/Wilkes-Barre following Sunday's 7-4 loss to the Houston Astros. Gil struggled in the outing, lasting four innings while allowing six runs on five hits, including two home runs. The 27-year-old has endured a difficult fifth MLB season after missing most of last year with an injury. His ERA has risen to 6.05, and he owns a 1.34 WHIP through four starts. Gil has struggled to limit hard contact and has not found consistent success with his new sinker. He will now look to reset in Triple-A and work his way back into the Yankees' rotation plans.

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Los Angeles Dodgers left-hander Blake Snell (shoulder) is scheduled to make his second rehab start for the Ontario Tower Buzzers on Tuesday as he works back from a left shoulder injury. Snell has been on the 15-day injured list since March 22 and has not appeared in a game this season. He threw 32 pitches in his first rehab outing, and a late May return remains possible if he continues to progress. When healthy, Snell remains one of baseball's most dominant left-handed starters. In his first season with the Dodgers in 2025, he posted a 2.35 ERA with 72 strikeouts in 61 1/3 innings across a limited sample size of 11 starts.

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Padres' 3B Manny Machado had five RBIs going 2-for-5 with two home runs in a 12-7 loss to Arizona on Sunday, Apr. 26.

Atlanta Braves pitcher Reynaldo Lopez is heading to the bullpen for now, according to Mark Bowman. The team is shifting Lopez to the pen so he can focus on his mechanical issues. The right-hander has walked 11 batters across his five starts and doesn't look sharp at the moment. The Braves want to keep JR Ritchie in the rotation, and Spencer Strider (oblique) is going to return soon. With that being said, Lopez is the odd man out at the moment. The right-hander is unlikely to offer any kind of reliable fantasy value while pitching out of the bullpen. It's unclear when Lopez will return to the rotation, so fantasy managers might want to look for another option.

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Toronto Blue Jays relief pitcher Louis Varland was tasked with once again pitching in the final frame. The right-hander earned his second save of the season on Saturday and was back out there a day later. Varland was solid as he tossed a scoreless inning while striking out two batters for his third save of the season. It wouldn't be shocking to see Varland unavailable on Monday after pitching in back-to-back games. The right-hander appears to be the favorite for saves in Toronto after notching back-to-back saves. Fantasy managers looking for a source of saves should consider adding Varland right now.

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Los Angeles Angels relief pitcher Jordan Romano has been designated for assignment by the organization on Sunday. The right-hander has been functioning as the closer for the Halos this season. He converted four saves across five scoreless innings of work to begin the season. After that, things got rough for Romano, who has allowed nine earned runs over his past five appearances. The Angels have decided to boot him off the roster after he allowed four earned runs on Saturday. The Angels will likely go with a committee approach in the bullpen until someone steps up and runs away with the role. Sam Bachman and Drew Pomeranz are names to watch as closer options.

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Los Angeles Angels relief pitcher Drew Pomeranz could be moving into a bigger role in the bullpen. On Sunday, closer Jordan Romano was designated for assignment by the organization. The right-hander was functioning as the closer for the Halos this season. He heavily struggled over the last handful of outings, so the team decided to move on. Without Romano on the roster, the Angels are likely going to go closer by committee for now. Pomeranz and Sam Bachman are likely the favorites to get the ball in high-leverage spots now. Fantasy managers should monitor this situation and scoop up whoever the Angels decide to lean on.

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Kansas City Royals relief pitcher Carlos Estevez (foot) was able to throw a two-up bullpen on Saturday and is scheduled to have hitters in Arizona on Tuesday. The right-hander has been sidelined since getting hit by a comebacker in late March. His recovery from his left foot contusion has been slow, but it sounds like Estevez is making progress. Estevez only made one appearance this season before landing on the Injured List. He allowed six earned runs on four hits across 0.1 innings of work. Lucas Erceg has been working as the closer while Estevez has been out. He has converted six of eight save chances, but holds a 5.23 ERA right now. Estevez could be back in the mix for saves once he's back with the Royals.

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Texas Rangers starting pitcher Jack Leiter (ankle) is ready to go and will make the start against the New York Yankees on Monday. Leiter suffered an ankle injury during his previous start versus the Pittsburgh Pirates on Wednesday. Luckily, it was a minor issue that isn't going to cost him anytime. The right-hander has struggled lately with a 6.91 ERA, 1.81 WHIP, and a 12/9 K:BB ratio over his last three starts. His first two starts of the season went well, but he hasn't been able to find the same success since then. Leiter will be a shaky streaming option against the Yankees' tough lineup.

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Los Angeles Dodgers catcher Will Smith (back) will miss his second straight game on Sunday in the series finale against the visiting Chicago Cubs due to back tightness, according to MLB.com. Dalton Rushing will be behind the plate to catch left-hander Justin Wrobleski while batting seventh against Cubs left-hander Shota Imanaga. Smith was originally expected to return on Sunday, but it appears the Dodgers will give him another day to recover before potentially returning for Monday's series opener against the visiting Miami Marlins. He'll be available off the bench on Monday and should avoid a stint on the injured list. The 31-year-old veteran backstop continues to be a great multi-category contributor at the weak catching position in fantasy, slashing .266/.337/.392 with three homers, 14 RBI, and 11 runs scored in his first 79 at-bats this year. Rushing has really turned it around at the plate so far in 2026 after struggling in 53 games as a rookie. He's gone 14-for-35 (.400) with seven home runs and 15 RBI. Despite the strong start, he's a tough sell for DFS lineups on Sunday in a tough lefty-on-lefty matchup against Imanaga.

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Arizona Diamondbacks shortstop Geraldo Perdomo (ankle) is not in the starting lineup in Mexico City on Sunday against the San Diego Padres, according to MLB.com. Perdomo is out of action for the two-game series finale in Mexico City after spraining his left ankle on Saturday. The D-backs aren't expecting Perdomo to land on the 10-day injured list, so he should have a very good chance of returning after an off day on Monday to face the Milwaukee Brewers on Tuesday. Jose Fernandez is making the start at shortstop and will hit sixth on Sunday against Padres right-hander Michael King. When active, the 26-year-old Perdomo is a must-start in fantasy baseball lineups. He's off to a .250/.350/.393 start with a .743 OPS, a homer, six RBI, 11 runs scored, and six stolen bases in his first 84 at-bats in 2026. Fernandez has looked even better at the plate in his first 21 MLB games, going 23-for-72 (.319) with two long balls and 11 RBI in 74 plate appearances.

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