Guest of the League
Lineup Changes
Berlin Buzz - Glenn VandeKolk
| Benched | QB | Brock Purdy SF | Owner | Wed Oct 30 8:21pm ET |
| Benched | WR | Calvin Austin III PIT | Owner | Wed Oct 30 8:21pm ET |
| Started | WR | Jerry Jeudy CLE | Owner | Wed Oct 30 8:21pm ET |
| Started | WR | Jakobi Meyers LV | Owner | Wed Oct 30 8:21pm ET |
| Benched | WR | Tre Tucker LV | Owner | Wed Oct 30 8:20pm ET |
| Started | WR | Chris Olave NO | Owner | Wed Oct 30 8:20pm ET |
Clermont Crushers - Mark Mullin Jr.
| Benched | D/ST | Indianapolis Colts IND | Owner | Fri Nov 1 11:37am ET |
| Started | D/ST | Seattle Seahawks SEA | Owner | Fri Nov 1 11:37am ET |
| Benched | RB | Najee Harris PIT | Commissioner | Wed Oct 30 10:10pm ET |
| Started | WR | Josh Downs IND | Commissioner | Wed Oct 30 10:10pm ET |
Cromarties Daycare - Michael Bennett
| Started | WR | Jaylen Waddle MIA | Owner | Fri Nov 1 11:37am ET |
| Benched | QB | Jameis Winston CLE | Owner | Fri Nov 1 11:37am ET |
| Benched | RB | David Montgomery DET | Owner | Fri Nov 1 11:37am ET |
| Benched | RB | Brian Robinson Jr. WAS | Owner | Fri Nov 1 11:37am ET |
| Benched | WR | Michael Pittman Jr. IND | Owner | Fri Nov 1 11:37am ET |
| Started | QB | Tua Tagovailoa MIA | Owner | Fri Nov 1 11:37am ET |
| Started | RB | J.K. Dobbins LAC | Owner | Fri Nov 1 11:37am ET |
| Started | WR | D.K. Metcalf SEA | Owner | Fri Nov 1 11:37am ET |
| Started | WR | Michael Pittman Jr. IND | Owner | Fri Nov 1 11:31am ET |
| Started | RB | D'Andre Swift CHI | Owner | Fri Nov 1 11:31am ET |
| Benched | WR | Ladd McConkey LAC | Owner | Fri Nov 1 11:31am ET |
| Benched | RB | J.K. Dobbins LAC | Owner | Fri Nov 1 11:31am ET |
| Benched | RB | Javonte Williams DEN | Owner | Tue Oct 29 10:03am ET |
| Benched | WR | Jaylen Waddle MIA | Owner | Tue Oct 29 10:03am ET |
| Benched | D/ST | Kansas City Chiefs KC | Owner | Tue Oct 29 10:03am ET |
| Started | QB | Jameis Winston CLE | Owner | Tue Oct 29 10:03am ET |
| Started | RB | Brian Robinson Jr. WAS | Owner | Tue Oct 29 10:03am ET |
| Started | WR | Ladd McConkey LAC | Owner | Tue Oct 29 10:03am ET |
| Started | D/ST | Chicago Bears CHI | Owner | Tue Oct 29 10:03am ET |
| Benched | QB | Tua Tagovailoa MIA | Owner | Tue Oct 29 10:03am ET |
Dayton Dragons - Michael Hirsch
| Started | D/ST | Seattle Seahawks SEA | Owner | Fri Nov 1 1:41pm ET |
| Benched | WR | Jordan Addison MIN | Owner | Tue Oct 29 10:38am ET |
| Started | WR | Keon Coleman BUF | Owner | Tue Oct 29 10:38am ET |
Fon Du Lac Flounder - Steve Lenz
| Benched | WR | Troy Franklin DEN | Owner | Thu Oct 31 6:39am ET |
| Started | WR | Kayshon Boutte NE | Owner | Thu Oct 31 6:39am ET |
| Benched | WR | George Pickens PIT | Commissioner | Wed Oct 30 10:12pm ET |
| Started | TE | Zach Ertz WAS | Commissioner | Wed Oct 30 10:12pm ET |
Great Falls Grizzlies - Tim McIntosh
| Benched | RB | Chuba Hubbard CAR | Owner | Thu Oct 31 12:19am ET |
| Started | TE | David Njoku CLE | Owner | Thu Oct 31 12:19am ET |
| Benched | WR | Deebo Samuel SF | Commissioner | Wed Oct 30 10:12pm ET |
| Started | RB | Alexander Mattison LV | Commissioner | Wed Oct 30 10:12pm ET |
Hurts Donut - Mike Sanchez
| Benched | RB | Justice Hill BAL | Owner | Tue Oct 29 2:36pm ET |
| Benched | WR | Brian Thomas Jr. JAX | Owner | Tue Oct 29 2:36pm ET |
| Benched | TE | George Kittle SF | Owner | Tue Oct 29 2:36pm ET |
| Started | RB | Rhamondre Stevenson NE | Owner | Tue Oct 29 2:36pm ET |
| Started | WR | DeAndre Hopkins KC | Owner | Tue Oct 29 2:36pm ET |
| Started | TE | Cade Otton TB | Owner | Tue Oct 29 2:36pm ET |
Kentucky Colonels - Bobby
| Benched | WR | Stefon Diggs HOU | Owner | Tue Oct 29 7:43pm ET |
| Benched | WR | Tyler Lockett SEA | Owner | Tue Oct 29 7:43pm ET |
| Benched | WR | Ricky Pearsall SF | Owner | Tue Oct 29 7:43pm ET |
| Benched | TE | Pat Freiermuth PIT | Owner | Tue Oct 29 7:43pm ET |
| Started | WR | Puka Nacua LAR | Owner | Tue Oct 29 7:43pm ET |
| Started | WR | Jaxon Smith-Njigba SEA | Owner | Tue Oct 29 7:43pm ET |
| Started | WR | Cedric Tillman CLE | Owner | Tue Oct 29 7:43pm ET |
| Started | TE | Taysom Hill NO | Owner | Tue Oct 29 7:43pm ET |
KY Gazelle - Sean Montgomery
| Started | D/ST | Houston Texans HOU | Owner | Thu Oct 31 8:52am ET |
Lexington GSDs - James Goatley
| Benched | WR | Christian Kirk JAX | Owner | Tue Oct 29 4:35pm ET |
| Started | RB | Zack Moss CIN | Owner | Tue Oct 29 4:35pm ET |
Lexington Labradors - Taylor Roberts
| Benched | WR | George Pickens PIT | Owner | Tue Oct 29 10:48am ET |
| Started | WR | Khalil Shakir BUF | Owner | Tue Oct 29 10:48am ET |
Milwaukee Maulers - Brian Moeller
| Benched | D/ST | Pittsburgh Steelers PIT | Owner | Tue Oct 29 10:59pm ET |
| Started | D/ST | Cincinnati Bengals CIN | Owner | Tue Oct 29 10:59pm ET |
| Benched | QB | Brock Purdy SF | Owner | Tue Oct 29 10:59pm ET |
| Benched | RB | Jordan Mason SF | Owner | Tue Oct 29 10:59pm ET |
| Benched | WR | Deebo Samuel SF | Owner | Tue Oct 29 10:59pm ET |
| Started | QB | Matthew Stafford LAR | Owner | Tue Oct 29 10:59pm ET |
| Started | WR | Jalen McMillan TB | Owner | Tue Oct 29 10:59pm ET |
| Started | WR | Xavier Worthy KC | Owner | Tue Oct 29 10:59pm ET |
| Started | TE | Trey McBride ARI | Owner | Tue Oct 29 10:59pm ET |
Montello Swamp Donkey's - Cougar Knudsen
| Benched | WR | Jordan Addison MIN | Owner | Tue Oct 29 9:05pm ET |
| Benched | WR | Tee Higgins CIN | Owner | Tue Oct 29 9:05pm ET |
| Started | WR | Jakobi Meyers LV | Owner | Tue Oct 29 9:05pm ET |
| Started | WR | Puka Nacua LAR | Owner | Tue Oct 29 9:05pm ET |
No Mercy - Shannon
| Benched | RB | Tank Bigsby JAX | Owner | Thu Oct 31 3:59pm ET |
| Started | RB | Tyrone Tracy Jr. NYG | Owner | Thu Oct 31 3:59pm ET |
Riverdawgs D2 - Brad Elder
| Benched | RB | Rico Dowdle DAL | Owner | Thu Oct 31 3:47am ET |
| Benched | TE | Pat Freiermuth PIT | Owner | Thu Oct 31 3:47am ET |
| Started | QB | Joe Flacco IND | Owner | Thu Oct 31 3:47am ET |
| Started | TE | Tyler Conklin NYJ | Owner | Thu Oct 31 3:47am ET |
Rosendale speed trap - Bill Van Ornum
| Started | WR | Darnell Mooney ATL | Owner | Thu Oct 31 7:59pm ET |
| Benched | WR | Alec Pierce IND | Owner | Thu Oct 31 7:59pm ET |
| Started | TE | Taysom Hill NO | Commissioner | Wed Oct 30 10:15pm ET |
| Started | WR | Cooper Kupp LAR | Commissioner | Wed Oct 30 10:15pm ET |
| Started | WR | Davante Adams NYJ | Commissioner | Wed Oct 30 10:15pm ET |
| Started | RB | Joe Mixon HOU | Commissioner | Wed Oct 30 10:15pm ET |
| Benched | TE | Luke Musgrave GB | Commissioner | Wed Oct 30 10:15pm ET |
| Benched | WR | Luke McCaffrey WAS | Commissioner | Wed Oct 30 10:15pm ET |
| Benched | WR | Mack Hollins BUF | Commissioner | Wed Oct 30 10:15pm ET |
| Benched | RB | Blake Corum LAR | Commissioner | Wed Oct 30 10:15pm ET |
San Diego Phenoms - Bakker
| Benched | TE | George Kittle SF | Commissioner | Wed Oct 30 10:16pm ET |
| Started | TE | Dalton Kincaid BUF | Commissioner | Wed Oct 30 10:16pm ET |
Tennessee Hilltoppers - Joseph Schings
| Started | RB | Bucky Irving TB | Owner | Fri Nov 1 11:16am ET |
| Started | QB | Bo Nix DEN | Owner | Fri Nov 1 11:16am ET |
| Benched | WR | Jalen Tolbert DAL | Owner | Fri Nov 1 11:16am ET |
| Started | D/ST | Detroit Lions DET | Owner | Thu Oct 31 2:41pm ET |
| Started | RB | Alexander Mattison LV | Owner | Wed Oct 30 3:48pm ET |
| Benched | WR | Michael Pittman Jr. IND | Owner | Wed Oct 30 3:48pm ET |
| Started | WR | Jalen Tolbert DAL | Owner | Tue Oct 29 9:27am ET |
| Started | WR | Cedric Tillman CLE | Owner | Tue Oct 29 9:27am ET |
| Benched | RB | Alexander Mattison LV | Owner | Tue Oct 29 9:27am ET |
| Benched | QB | Spencer Rattler NO | Owner | Tue Oct 29 9:27am ET |
Waukesha Chimps - Brady Moeller
| No starting lineup changes performed this week. |
Winnebago Muskrats - Tim Splittgerber, Jason J.
| Benched | QB | Geno Smith SEA | Owner | Wed Oct 30 4:34pm ET |
| Benched | RB | Jordan Mason SF | Owner | Wed Oct 30 4:34pm ET |
| Benched | WR | Jaylen Waddle MIA | Owner | Wed Oct 30 4:34pm ET |
| Started | QB | Jayden Daniels WAS | Owner | Wed Oct 30 4:34pm ET |
| Started | RB | Rachaad White TB | Owner | Wed Oct 30 4:34pm ET |
| Started | WR | Josh Downs IND | Owner | Wed Oct 30 4:34pm ET |
