Arizona Cardinals kicker Matt Prater (knee) is expected to be inactive for Week 6 against the Green Bay Packers, according to NFL Network's Ian Rapoport. If confirmed, it will be the veteran kicker's second consecutive absence. He had been perfect through four games, converting all 10 of his extra point attempts and all six of his field goal tries. The Cardinals have once again elevated Chad Ryland to kick in Prater's place. In his season debut last week, Ryland went 3-for-4 on field goals and also made his lone extra point attempt.

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Jacksonville Jaguars tight end Evan Engram (hamstring) is officially active for Sunday morning's game against the Chicago Bears in London. The veteran tight end, who had been listed as questionable after logging three limited practices, returns to game action for the first time since Week 1. In the season opener, he was held to just one catch on four targets. However, Jacksonville has done a better job of incorporating its tight ends lately, relying on Brenton Strange for nine catches, 55 yards, and two touchdowns over the last three weeks. Engram is an effective playmaker who ranks among the top 12 tight ends for this week in fantasy football.

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Jacksonville Jaguars wide receiver Gabe Davis (knee) is officially active for Week 6 against the Chicago Bears in London. Davis had been listed as questionable after logging three consecutive limited practices, but in the end, he'll avoid his first absence of the 2024 season. Through five games this year, Davis has caught 12 of 25 targets for just 159 yards through the air. Despite handling a heavy snap share, he has seen reduced opportunities in Jacksonville's offense, including over the last three weeks. He can be kept out of lineups fantasy lineups once again in Week 6, especially now that Evan Engram (hamstring) is back and set to command significant volume.

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Las Vegas Raiders kicker Daniel Carlson will have to hope for his team to get drives into his field-goal range when they take on the Pittsburgh Steelers in Week 6, though that could be wishful thinking. The Steelers have allowed the fourth-least fantasy points per game to opposing kickers this season, mainly due to their strong defense. The Las Vegas offense does not match up well with any good defense, so we could see another game in which Carlson has too few kick opportunities to be fantasy-relevant. He's made 8/10 of his field goals and is a perfect eight-for-eight on extra points, but that's not been enough volume to make him worth starting in fantasy leagues. He should remain on waivers as he is the 27th-ranked kicker in RotoBaller's Week 6 fantasy football rankings.

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Jacksonville Jaguars wide receiver Gabe Davis (knee) is likely to suit up for Sunday's overseas matchup with the Chicago Bears. The wideout has battled various ailments over the last few weeks. However, a knee injury forced him to practice in a limited capacity throughout the week. With that in mind, Davis hasn't had more than three catches in a game this season. He also hasn't scored a touchdown. With Evan Engram (hamstring) also expected to play in London, Davis' chances of staying involved consistently during the contest aren't favorable. Fantasy managers should keep him out of the starting lineup, assuming he officially gets the green light to get on the field.

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Indianapolis Colts quarterback Anthony Richardson (oblique) continues to trend toward returning for Sunday's meeting with the Tennessee Titans. He's currently listed as questionable. However, according to NFL Media's Ian Rapoport, the signal-caller should play if he has a "solid pre-game workout." Despite entering the 2024-25 campaign with plenty of hype, Richardson hasn't delivered, throwing for 654 yards, three touchdowns, and six picks while completing just 50.6% of his throws. As a result, he's a risky fantasy option no matter the opponent, although his outlook will improve slightly if Michael Pittman Jr. (back) and Josh Downs (toe) suit up in Week 6. Fortunately, both players are expected to get on the field.

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According to NFL Media's Ian Rapoport, Las Vegas Raiders running back Zamir White (groin) is "considered a long-shot to play" in Sunday's game against the Steelers. The 25-year-old missed a few practices during the week, although he was on the field in a limited capacity on Friday. However, it appears he'll miss his second straight game, so his next chance to suit up will be for the Week 7 meeting with the Los Angeles Rams. Without White in the equation, Alexander Mattison should handle most of the carries out of the backfield, with Ameer Abdullah picking up some of the slack as his backup. But no matter who is atop the depth chart at the position, they are expected to have a challenging day against one of the most efficient run-stop units in the National Football League, something for fantasy managers to consider before setting their lineups.

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Denver Broncos running back Audric Estime (ankle) was activated from the IR heading into Sunday's divisional clash with the Chargers. The 21-year-old rookie made his only appearance of the 2024-25 campaign in Week 1 versus Seattle. Estime had only two carries for 14 yards in that one. He also injured his ankle, putting him on the shelf. With that in mind, Estime's fantasy potential is severely limited in Week 6, assuming he sheds his questionable designation, considering Javonte Williams and Jaleel McLaughlin are the top options out of the backfield. However, the Broncos offense has struggled this season, so anyone on that side of the ball is hard to trust.

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The Arizona Cardinals elevated kicker Chad Ryland from the practice squad heading into the Week 6 meeting with the Packers. With Matt Prater (knee) questionable, the team may look to Ryland to handle the kicking duties. He looked good in Week 5 against the 49ers, making three of his four field goal attempts, one of which secured the win for the Cardinals. However, with rain and wind in the forecast in Green Bay, fantasy managers in need of a kicker may want to look elsewhere.

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According to ESPN's Adam Schefter, Las Vegas Raiders wide receiver Davante Adams (hamstring) "could wind up staying" with the team. Schefter didn't elaborate. However, it adds another dynamic to what has already been a volatile situation. The wideout will miss another game on Sunday due to a hamstring injury, with many still believing his days with the Raiders are over. But at this point, fantasy managers aren't as concerned with who he is playing for as long as he gets back on the field. As far as the Week 6 meeting with the Steelers is concerned, Jakobi Meyers (ankle) is doubtful, so it could be a rough day for Aidan O'Connell. Still, the door is open for Tre Tucker and DJ Turner, who both logged over 50 snaps in Week 5, to get more involved. Alex Bachman and Tyreik McAllister may also enter the equation, although Brock Bowers still has the best chance of being the top fantasy pass-catcher for Vegas in Week 6.

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Dynasty | 49ers wide receiver Jauan Jennings had just three catches for 27 yards in a win against Seattle Thursday night. Dynasty Analysis: Much like his teammate Brandon Aiyuk, Jennings has had one blow-up game (11/175/3) and four clunkers that have resulted in just 14 catches for 229 scoreless yards. Jennings is looking like a boom or bust player each week and dynasty managers are going to need to feel pretty desperate to trust him on a weekly basis at this point.

Dynasty | Seahawks running back Kenneth Walker had 32 rushing yards, eight catches and 37 receiving yards with one touchdown in a loss against the 49ers. Dynasty Analysis: The yardage totals for Walker weren't good but eight catches and a touchdown made his night a good one, at least in PPR leagues. Even better, Walker continued to dominate backfield touches as he had 22 compared to the six from Zach Charbonnet. Walker is a prime trade target for a contending dynasty team as he's become one of the more consistent running backs in the game.

Dynasty | Seahawks wide receiver DK Metcalf had three catches for 48 yards in a loss against the 49ers on Thursday night. Dynasty Analysis: Metcalf had 11 targets, but he and Geno Smith are just not on the same page. After three straight 100-yard games, Metcalf now has just seven catches for 103 scoreless yards over his last two games. He did have a long touchdown called back because of a penalty, but things seem to be going sour for Seattle in a hurry as they've lost three straight and seem to be losing their way a bit. Metcalf will likely bounce back but this is notable in future weeks as lineup decisions are being made.

Indianapolis Colts wide receiver Michael Pittman Jr. (back) plans to play Sunday in the team's Week 6 road matchup against the Tennessee Titans. A few days ago, there was talk that Pittman could miss multiple weeks with a back injury and began the week with back-to-back non-participant designations at practice. His fortune changed on Friday when he was able to log a limited session, and he is reportedly traveling with the team to Nashville ahead of the divisional tilt, per Stephen Holder of The Athletic. It's excellent news for the Colts, who should also have second-year wide receiver Josh Downs (toe) and quarterback Anthony Richardson (oblique) active for the contest as well. Reports are that the 27-year-old will "play through" the nagging back injury, so it's possible he is operating at less than 100% and could have his snap count monitored. Tennessee's defense has been difficult for opposing offenses this season, so expectations should be tempered due to his health and the poor matchup.

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Indianapolis Colts wide receiver Josh Downs (toe) is expected to be active for the team's Week 6 road matchup against the Tennessee Titans. Despite logging two DNPs this week and being listed as questionable, the second-year wideout will reportedly suit up, according to Stephen Holder of The Athletic. Teammate Michael Pittman Jr. (back) traveled with the team and also plans to play in the contest against the Titans. Downs has been a PPR monster over the last two weeks, racking up 17 catches, 151 yards, and a touchdown on 21 targets. However, it's worth noting that most of this production came with veteran quarterback Joe Flacco under center in stead of second-year QB Anthony Richardson (oblique). Richardson is also slated to be active for Sunday's outing, so the 23-year-old wideout could return to a lower-volume role. Still, he could see more work than usual with Pittman dinged up. Regardless, the Titans' defense has been one of the more staunch units against opposing offenses, so look for Indy's unit to have their hands full.

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The Detroit Lions and running back David Montgomery have agreed to a two-year $18.25 million extension, locking the veteran RB up through the 2027 season, per Adam Schefter. Montgomery had two years remaining on the three-year $18 million deal he inked in 2023, but the team saw fit to extend an integral part of their offense. The new contract includes $10.5 million in new guaranteed money, and Detroit handcuffs him and backfield mate Jahmyr Gibbs for the foreseeable future. Since 2019, the former third-round pick's 43 rushing scores are good for ninth-most in the league. The 27-year-old has been one of the more consistent fantasy backs this season despite fluctuating yardage outputs, scoring a touchdown in each of his first four outings. He'll look to keep that streak going in Week 6 on the road against the Cowboys.

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Cleveland Browns running back Nick Chubb (knee) is scheduled to make his 2024 debut next Sunday when his team hosts the Cincinnati Bengals in a home matchup, per Mary Kay Cabot of Cleveland.com. It will be his first regular-season action since Week 2 of last season when he was forced from the Browns' contest against the Pittsburgh Steelers after suffering a gruesome, complex knee injury. It's unclear what capacity that will be in, and it is fair to wonder whether or not he'll be on a snap count, but it's a remarkable feat for the 28-year-old. For one more week, it will be running backs D'Onta Foreman and Jerome Ford shouldering the load in the backfield before the former second-round pick's return. When that comes to pass, Chubb will likely make this backfield a three-man rotation until he is healthy -- or effective -- enough to siphon touches away from his teammates. That duo will face an Eagles squad in Week 6 that's let up the eighth-fewest yards on the ground to opposing defenses (515) but the third-most yards per carry (5.0).

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Indianapolis Colts rookie wide receiver Adonai Mitchell caught four of his seven targets for 38 yards in the team's Week 5 loss to the Jacksonville Jaguars. Despite a decent target share, Mitchell saw a very low snap share, playing a total of just 19 in the game. With Michael Pittman Jr. (back) and Josh Downs (toe) trending to play, Mitchell will likely see a similar snap share again in Week 6. On top of that, Mitchell and the Colts will be up against the Titans' secondary, a unit that's allowed the lowest receiving yards/game as well as the fewest fantasy points to opposing WRs. Mitchell is better left on the bench in Week 6.

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Indianapolis Colts quarterback Joe Flacco had an outstanding Week 5 performance, completing 33 of his 44 passes for 359 yards in the team's loss. Flacco's starting status for Week 6 against the Titans is up in the air, with QB Anthony Richardson (oblique) tracking to play but still a game-time decision. If Flacco were to start, he would make for a deeper streaming option, with the Titans secondary allowing the fewest passing yards this season at a 124/game average. Fantasy managers in 2QB/Superflex leagues should stay up to date on the news on Sunday morning, should they need a last-minute replacement.

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Indianapolis Colts wide receiver Alec Pierce popped in the team's Week 5 loss, grabbing all three of his targets for 134 yards and a touchdown. He'll now gear up for a Week 6 matchup against the Tennessee Titans, the team allowing the fewest points to opposing WRs this season. While Pierce has led the team in yards with 386, he comes in fourth in total target share at 12.1%. On top of that, reports suggest that the Colts will be starting QB Anthony Richardson (oblique) in Week 6, which may lower the team's passing volume as opposed to if they were to start QB Joe Flacco. While there remains the possibility that Pierce can catch a few deep shots like he has in weeks past, it's a hard thing to bank on in such a tough matchup. Fantasy managers can view Pierce as a WR4/5 option in Week 6, with him currently slated as the WR46 in our staff's half-PPR rankings.

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