Toronto Blue Jays closer Jeff Hoffman struggled again Tuesday, blowing his third save of the season in a 9-7 extra-innings win against the Brewers. Hoffman entered the ninth inning with a 6-4 lead but allowed two runs on two hits, forcing extra innings. The 33-year-old is now two for five in save chances, a large concern for a contender. He owns a 1.80 WHIP and 4.32 ERA across nine appearances. Hoffman has not found consistency since arriving from Philadelphia, and his grip on the closer role is weakening. Toronto could begin to consider alternative options if these struggles continue.

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Milwaukee Brewers reliever Trevor Megill took another step backward Tuesday, allowing three runs in one inning during a 9-7 loss against the Blue Jays to blow his first save of the season. Megill has now given up runs in three of his six outings, and his ERA has risen to 14.40. The 32-year-old opened the season as the clear closer, but early inconsistency is raising concern. His strikeout rate has dipped after last season's breakout, and reduced swing-and-miss ability has led to more hard contact. Megill has a track record that suggests improvement is possible, but Milwaukee may explore alternatives if struggles continue.

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Los Angeles Dodgers left-hander Alex Vesia delivered a perfect inning in Tuesday's 2-1 victory vs. the Mets, earning his second save of the season. Alex Vesia struck out all three batters he faced and has converted both of his save chances. The 30-year-old has yet to allow a run, posting a 0.68 WHIP with nine strikeouts across 7 innings. He has limited pull-side contact effectively, holding hitters to a 13.3 percent rate, supporting his early success and pointing to sustainable production. Vesia continues to carve out a high-leverage role and is positioning himself as a strong closer handcuff option out of the Dodgers bullpen.

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Minnesota's SP Mick Abel recorded 10 strikeouts in 7 innings with the win in a 6-0 win over the Red Sox on Tuesday, Apr. 14.

Yankees' SP Ryan Weathers recorded 10 strikeouts in 5 innings but took the loss in a 7-1 loss to the Angels on Tuesday, Apr. 14.

Arizona Diamondbacks manager Torey Lovullo said that he has second baseman Ketel Marte (back) in the starting lineup for Wednesday's game against the Baltimore Orioles as of now, according to Diamondbacks reporter Jody Jackson. The Snakes scratched Marte from Tuesday's starting lineup in Baltimore as a precaution due to lower-back tightness, but apparently, he's already feeling much better. Fantasy managers have to be pretty stoked that Marte will end up missing just one game. The three-time All-Star is a must-start anytime he's in Arizona's lineup. Marte is off to a .212 (14-for-66) start to the 2026 season, his 12th in the league, but he's been heating up of late and has four homers and nine total RBI in 72 plate appearances. If he indeed returns on Wednesday in the series finale at Camden Yards, Marte will be facing right-hander Kyle Bradish. He's only faced Bradish twice in his career and has two hits and an RBI.

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Cincinnati Reds reliever Tony Santillan is off to a strong start to the 2026 season, as he's recorded 10 strikeouts and has yet to allow an earned run across his first eight innings pitched (eight games). With the news that Reds closer Emilio Pagan (hamstring) is being evaluated for a hamstring injury, Santillan could be in line to assume the ninth-inning role in Cincinnati. The 29-year-old was one of the Reds' best high-leverage arms in 2025, recording a 2.44 ERA and 1.11 WHIP with 75 strikeouts across 73 2/3 innings (80 games). Santillan also picked up seven saves and has 11 saves in his big-league career, so he has some experience as a closer. If Pagan ends up missing time, Santillan would immediately become a priority target on the waiver wire for fantasy managers.

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Minnesota Twins starting pitcher Mick Abel was excellent against the Boston Red Sox on Tuesday, pitching seven strikeout innings with 10 strikeouts and earning his first win of the season in his team's 6-0 victory. Abel allowed just four hits and did not allow a walk. Across his first four appearances (20 1/3 innings) of 2026, the 24-year-old has pitched to a 3.98 ERA and 1.59 WHIP with 23 strikeouts. However, since allowing nine earned runs over his first 7 1/3 innings of the year, Abel has now thrown 13 straight scoreless frames. Abel's walk rate is still 10.8% even after his most recent start against the Red Sox, so control is an issue. Still, if he can limit free passes, Abel has good enough stuff to consistently generate strikeouts and work deep into games. He profiles as a priority waiver wire target ahead of his next scheduled start against the New York Mets next Tuesday.

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Cincinnati Reds manager Terry Francona said that closer Emilio Pagan (hamstring) is getting his hamstring checked out after earning the save in his team's 2-1 win over the San Francisco Giants on Tuesday, per Jeremy Rauch of Fox 19 Cincinnati. Pagan pitched a scoreless ninth inning with a strikeout for his fifth save of the season, but is apparently dealing with some discomfort that will need monitoring. The 34-year-old is five-for-six on save chances so far this season and has pitched to a 4.82 ERA and 1.32 WHIP with nine strikeouts across 9 1/3 innings pitched. If Pagan is forced to miss time, Cincinnati right-handers Tony Santillan and Graham Ashcraft could be the favorites to move into the ninth-inning role for the Reds.

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Milwaukee Brewers right-handed pitcher Brandon Sproat (knee) is slated to rejoin the team's starting rotation on Thursday against the Miami Marlins, according to Jack Stern of Brewer Fanatic. Sproat's first appearance of 2026 came as a starter, but his most recent two have come in long relief. The 25-year-old was also evaluated for a knee injury after his most recent outing on Saturday, but it appears as though he has avoided missed time. Sproat has struggled across 10 1/3 innings so far this season, recording a 10.45 ERA and 2.32 WHIP with 10 strikeouts. Command has been the biggest issue, as he's allowed 10 walks. However, Sproat allowed just one run across 3 2/3 innings pitched in his last appearance. He remains a well-regarded prospect with upside who could be a worthy target on the waiver wire for fantasy managers.

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Boston Red Sox first baseman Willson Contreras (back) has been removed from his team's Tuesday night matchup against the Minnesota Twins due to low back tightness, per Tim Healey of The Boston Globe. Contreras was hitless in two at-bats before exiting the game. The 33-year-old is off to a strong start to his first season with Boston, hitting .298/.444/.491 with three home runs, 11 RBI, and nine runs scored. It doesn't appear as though this latest back ailment is particularly serious, but it will be worth monitoring for fantasy managers nonetheless. Contreras was replaced by utility man Andruw Monasterio on Tuesday, so Monasterio could be the favorite to see an increase in playing time if Contreras ends up requiring a stint on the injured list.

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Philadelphia Phillies right-hander Zack Wheeler (shoulder) is nearing his 2026 season debut. The 35-year-old three-time All-Star allowed three earned runs on four hits while walking none and striking out nine in 5 2/3 innings for Double-A Reading on Tuesday. It was Wheeler's fourth rehab start already, and he got up to 95 mph on Tuesday after sitting in the low-90s his last time out. It's an encouraging sign that Wheeler is getting closer to returning from surgery for thoracic outlet syndrome last year. He plans to make another start for Reading on Sunday, which could be his last before the Phillies activate him from the 15-day injured list to rejoin the big-league starting rotation. Wheeler was an All-Star in both 2024 and 2025, and he has 200-plus strikeouts in three of the last five years with the Phillies. Although he's much riskier in 2026 coming off surgery for thoracic outlet syndrome, he absolutely should be stashed in all formats with the hope that he can return to his pre-injury ace form.

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Boston Red Sox first baseman Triston Casas (abdomen, knee) is dealing with an abdominal strain and will be shut down until he feels better, according to Tim Healey of The Boston Globe. The good news is that Casas' abdominal strain is not related to his rib-cage issue from two years ago, according to manager Alex Cora. Once Casas is feeling better, he'll have to go through a spring training-style buildup, so it's going to be a while before we see him back in the big leagues. The 26-year-old left-handed slugger only made it through 29 games in 2025 before suffering a season-ending patellar tendon tear. Casas hit only .182/.277/.303 with three homers and 11 RBI in those 29 games, too. In 132 games in 2023 in his first full season in the majors, Casas hit .263 with 24 home runs and 65 RBI in 502 plate appearances, but injuries have wrecked his last two seasons. Willson Contreras is locked in at first base for the BoSox now, so when Casas is finally ready to make his 2026 debut, he could be battling for at-bats in the designated-hitter role.

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Imaging on Houston Astros right-hander Tatsuya Imai's right arm came back clean and "positive," according to Chandler Rome of The Athletic. The Astros will try to increase his arm strength before Imai resumes throwing. The 27-year-old is definitely struggling in his adjustment from Nippon Professional Baseball to Major League Baseball. The Astros placed him on the 15-day injured list on Monday with right-arm fatigue just three starts into his career in the big leagues. And in his first three starts (8 2/3 innings), Imai has struggled, allowing seven earned runs on seven hits while walking 11 and striking out 13. It's certainly not what fantasy managers were envisioning for Imai to begin his Astros tenure in 2026. The good news, though, is that Imai isn't dealing with any structural damage, and it's still early in his first year in MLB. Don't expect a quick return to Houston's starting rotation, though, as the Astros look to build up his arm strength, which will take time.

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San Diego Padres outfielder Fernando Tatis Jr. is starting in right field and will bat in the two-hole for the Friars for Tuesday's series opener against the visiting Seattle Mariners and right-hander Bryan Woo at Petco Park, according to MLB.com. The Padres moved Tatis to second base in the last two games of the four-game series against the Colorado Rockies over the weekend, and he went 5-for-9 at the plate with a double, an RBI, and a stolen base in those two games to break out of a little early-season funk as a hitter. The 27-year-old Dominican All-Star is hitting .242 (15-for-62) on the season with six RBI, six runs scored, and four stolen bases in 16 games played. Tatis is still searching for his first home run of the season. If he were to play enough games at the keystone to pick up second base eligibility, it would make Tatis more valuable to fantasy managers. He'll look to keep it up offensively on Tuesday against Woo, whom he's hitting .333 against with a 1.333 OPS, two home runs, and two RBI against in nine career at-bats.

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Arizona Diamondbacks second baseman Ketel Marte (back) is a late scratch from Tuesday's game against the Baltimore Orioles. Marte was pulled out of the lineup minutes before first pitch. There should be another update on his status following Tuesday's game, but for now, his injury is being called lower back tightness. Fantasy managers should consider Marte as day-to-day until another update is provided. Ildemaro Vargas will take over at second base and bat in the leadoff spot against left-hander Trevor Rogers.

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Texas Rangers outfielder Wyatt Langford (quad) is back in the starting lineup ahead of Tuesday's game against the Athletics. Langford is returning after missing the last three games due to a minor quad issue. Luckily, Langford was able to avoid a trip to the Injured List and only missed a few contests. The Rangers will ease him back into action by placing him at designated hitter against southpaw Jeffrey Springs on Tuesday. It has been a slow start to the season for Langford, but hopefully he can turn it around now that he's fully healthy. Fantasy managers should make sure to get him active in their lineups ahead of first pitch.

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San Diego Padres starting pitcher Nick Pivetta (elbow) was placed on the 15-day Injured List, retroactive to April 13. Pivetta will head to the shelf after being lifted from Sunday's start against the Colorado Rockies due to elbow stiffness. The Padres are calling the injury right elbow inflammation, but he'll likely undergo further testing to determine the severity of the issue. In a corresponding move, right-hander Alek Jacob has been recalled from Triple-A El Paso. Jacob should provide bullpen depth with Matt Waldron set to replace Pivetta in the rotation. Waldron hasn't pitched this season, but is scheduled to start against the Los Angeles Angels on Friday. The 29-year-old should be viewed as a risky streaming choice for that one.

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Detroit Tigers infielder Colt Keith (rest) is out of the starting lineup ahead of Tuesday's game against the Kansas City Royals. Fantasy managers don't need to panic as this appears to be a rare rest day for Keith. The Tigers will opt to go with Javier Baez at shortstop and Kevin McGonigle at the hot corner with tough lefty Cole Ragans on the mound for Kansas City. The expectation is that Keith will be back in the lineup on Wednesday. Keith has been great with the bat, slashing .340/.375/.472 through 15 games this season.

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Houston Astros first baseman Christian Walker (leg) is in the starting lineup ahead of Tuesday's game against the Colorado Rockies. Walker appears to be back to 100 percent after missing a game over the weekend due to a leg issue. Since returning to the lineup, Walker is 0-for-6 over the last two games. He'll bat fifth and cover first base ahead of Tuesday's contest. Walker has struggled with only five hits in his last seven games. Fantasy managers in season-long formats can get him active, but Walker won't be an ideal DFS option for Tuesday's slate.

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