New York Yankees first baseman Ben Rice is hitting cleanup on Opening night on Wednesday at Oracle Park against the San Francisco Giants and right-hander Logan Webb, according to MLB.com. Rice is entrusted in the middle of New York's potent lineup after breaking out in 2025 to the tune of a .255/.337/.499 slash line, .836 OPS, 26 home runs, 65 RBI, and 74 runs scored in 530 plate appearances over 138 regular-season games. He has only faced Webb three times in his career and has one hit and an RBI. Not only does Rice have 30-homer potential at Yankee Stadium from the left side of the plate, but he also has catcher eligibility for fantasy managers. In 16 Grapefruit League games in spring training, Rice went 11-for-46 (.239) with two home runs, five RBI, seven runs scored, and a stolen base. He's as good a DFS selection on Opening night in San Fran as any Yankees hitter.

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San Francisco Giants outfielder Heliot Ramos is starting in left field and batting sixth for the Giants on Opening night at Oracle Park on Wednesday against the visiting New York Yankees and left-hander Max Fried, according to MLB.com. It's a tough matchup, and many DFS managers won't feel comfortable pulling the trigger on Ramos in the first game of the regular season, especially since he's hitless in eight career at-bats against Fried. On a random note, Ramos becomes the first Giants left fielder to make back-to-back Opening Day starts since Barry Bonds in 2007. The 26-year-old former first-rounder in 2017 has back-to-back 20-homer seasons for the Giants as well, and he also cut his strikeout rate considerably in 2025. But with Luis Arraez now in town and hitting leadoff, Ramos' counting stats could take a big hit while residing further down the Giants' batting order. Ramos might have already reached his fantasy ceiling, especially at pitcher-friendly Oracle Park.

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San Francisco Giants outfielder Jerar Encarnacion is not in the team's starting lineup on Opening Day on Wednesday evening at Oracle Park against the visiting New York Yankees and left-hander Max Fried, according to Shayna Rubin of the San Francisco Chronicle. Rafael Devers is serving as the Giants' designated hitter, with infielder Casey Schmitt making the start at first base. The 28-year-old Encarnacion could find playing time difficult to come by again in 2026 after playing in just 19 games in 2025 and slashing .200/.214/.364 with two home runs, seven RBI, and five runs scored in just 56 plate appearances. He dealt with hamstring, hand, and oblique injuries. Encarnacion makes very loud contact when he impacts the baseball, but he struggles to make consistent contact and has a history of injuries. He's out of minor-league options and will have to produce when he's given the opportunities in 2026 if he wants to stick around in the Giants' organization. Encarnacion has hit just .216 with 10 homers and 40 RBI in his 77 big-league games over three seasons with the Giants and Marlins.

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The Atlanta Braves placed catcher Sean Murphy (hip) on the 10-day injured list on Wednesday with right-hip labrum repair, according to MLB.com. Murphy was always expected to begin the 2026 regular season on the shelf, and now it's official. He underwent surgery on his right hip in September of last year and isn't expected to be ready to make his season debut this year until sometime in May. It obviously makes Murphy much less attractive in fantasy baseball, especially with Drake Baldwin and Jonah Heim totally capable of handling the catching duties in Atlanta. The 31-year-old veteran backstop was able to take on-field batting practice on March 9, but he still has plenty of boxes to check in his rehab, including defensive work and running. Murphy was a first-time All-Star in his first year in Atlanta in 2023, but he has played in a combined 166 games the last two years while hitting just .197/.293/.384 with a .676 OPS in 601 plate appearances. When healthy, a lesser role could be coming for Murphy between catcher and designated hitter, and there's no guarantee the pop returns after having hip surgery.

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The Seattle Mariners placed shortstop J.P. Crawford (shoulder) on the 10-day injured list on Wednesday with right-shoulder inflammation, according to Daniel Kramer of MLB.com. Crawford received a cortisone injection last week for a shoulder injury that he's dealt with since the start of spring training in February. He managed to play in seven Cactus League games, though, going 2-for-16 (.125) with three RBI and a stolen base. The good news for the M's is that they could have their starting shortstop back when he's eligible to come off the IL on Wednesday, April 1. Until then, Leo Rivas will have added value in AL-only leagues as middle-infield depth as the starter at the 6 for Seattle. Crawford's injury isn't serious, but it's another knock on the former first-rounder and his limited fantasy upside. He had double-digit home runs (12) for just the second time in his nine-year MLB career in 2025, and he's never had double-digit stolen bases in 930 career games.

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The Seattle Mariners placed right-hander Bryce Miller (oblique) on the 15-day injured list on Wednesday with a left-oblique strain, according to MLB.com's Daniel Kramer. Miller only made one appearance during spring training after injuring his oblique late last month. The good news, though, is that the 27-year-old hasn't had any setbacks after throwing a couple of bullpen sessions in camp. Miller still needs a couple of weeks to build his arm back up, but barring a setback, he figures to rejoin Seattle's starting rotation before the end of April. In the meantime, Emerson Hancock will take Miller's spot in the team's rotation. The former fourth-round pick of the Mariners in 2021 out of Texas A&M went 12-8 with a 2.94 ERA, 0.98 WHIP, and 171:45 K:BB in 31 starts in his second big-league season before dealing with injuries and posting a 5.68 ERA and 1.41 WHIP in just 18 starts in 2025 due to injuries. Miller is pitching with a bone spur in his right elbow as well, making him more of a risk in 2026, but he's still a worthwhile IL stash for his upside in mixed fantasy leagues.

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St. Louis Cardinals outfielder Lars Nootbaar (heels) was placed on the 60-day injured list on Wednesday. This means the left-handed hitter will be out until at least late May as he recovers from offseason surgery to both of his heels. The team was hoping to avoid a 60-day IL stint, but instead, Nathan Church, Thomas Saggese, and Jose Fermin will compete for playing time in left field to begin the year. When Nootbaar returns, he does offer some pop after having reached at least 12 home runs the last four seasons, along with a solid OBP thanks to a strong walk rate, but you may be able to find higher-upside options on the waiver wire even when he's back in the lineup.

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Baltimore Orioles second baseman Jackson Holliday (hand) was placed on the 10-day injured list on Wednesday. The left-handed slugger is working his way back from a broken hamate bone that he suffered back in February and has been making steady progress, even taking live batting practice last week. A minimal stay on the IL appears to be in order, so expect an announcement of a rehab assignment soon, which would likely take place at Triple-A Norfolk. The former first overall draft pick debuted in 2024 and showed signs of improvement in 2025, dropping his K% from 33.2 percent to 21.6 percent as his contact rate went from 70.3 percent to 78.7 percent, resulting in a wRC+ that went from 62 to 96. If the 22-year-old can continue to improve, he could be on the verge of a very fantasy-friendly third season in the big leagues.

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Baltimore Orioles outfield prospect Dylan Beavers (knee) said he "peeled back" on activity that irritated his right knee/quadriceps and has been receiving treatment, according to Jake Rill of MLB.com. Beavers had a full work day on Tuesday, including running the bases, and "feels ready to go" for Opening Day on Thursday against the Minnesota Twins. In 11 Grapefruit League games this spring before his injury, Beavers went 7-for-33 (.212) with a homer, four doubles, two RBI, four runs scored, one walk, and 10 strikeouts in 34 plate appearances. He played in 35 games for the O's in his MLB debut in 2025, hitting .227 (25-for-110) with four homers, 14 RBI, 16 runs scored, and two stolen bases in 137 plate appearances. It remains to be seen how big a role Beavers will have in the outfield in Baltimore to begin his first full year in the big leagues, but he's a high-floor prospect who had a .304 batting average, 18 home runs, and 23 steals in 94 games at Triple-A Norfolk in 2025.

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New York Yankees starting pitcher Clarke Schmidt (elbow) is expected to begin throwing bullpen sessions at the end of March and could progress to throwing to live hitters in April if all goes well. The right-hander is continuing his recovery from Tommy John surgery that he underwent last July, and his current track puts him on pace to return to the big league mound sometime in the second half of the season, so long as he does not encounter any setbacks. The former first-round draft pick has been a relatively effective pitcher for the Yankees over the last few years, but he also missed a lot of time in 2024 due to injury. The 6-foot-1 hurler recorded a 3.07 ERA, 1.14 WHIP, and 15.8 percent K-BB% in 30 starts between 2024 and 2025, and if he can regain that form, he could be a worthy stash candidate or waiver add later in the year.

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Los Angeles Dodgers first baseman Freddie Freeman batted fifth in the lineup in Monday's Cactus League game against the Angels with left-hander Reid Detmers on the mound, something manager Dave Roberts stated he would do with his lineup against southpaws to begin the season. Freeman will typically bat fourth, and catcher Will Smith will bat fifth, but against lefties, they'll be swapped. It is somewhat of a head-scratcher given Freeman's ability to hit lefties just fine, even better than Smith, both for his career and in 2025, so there hasn't been a dropoff in effectiveness from the veteran slugger. We'll see how long the change holds up, but regardless, Freeman and Smith should remain plenty productive in a loaded Los Angeles lineup.

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Boston Red Sox first baseman Triston Casas (knee) was placed on the 10-day injured list on Wednesday. This was not a surprise as the 6-foot-4 slugger was unable to participate in any Grapefruit League action as he continues to recover from a ruptured left patellar tendon that he suffered in 2025. He recently faced live hitters and has been cleared to run the bases and slide, but with no rehab assignment scheduled yet, it's not certain when he might be able to return to the majors. Mid-to-late May is probably a good estimate based on the usual timeline, but there is no rush as the team acquired Willson Contreras in the offseason to man first base, and before his injury last year, the left-handed hitter was slashing just .182/.277/.303, so they may want to make sure he's fully knocked the rust off before he competes for at-bats with the big league club. The former first-rounder does have some power, though, as he belted 24 home runs in 2023 in 132 games, so the 26-year-old's progress is certainly worth monitoring for fantasy.

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The Atlanta Braves placed right-hander Spencer Strider (oblique) on the 15-day injured list on Wednesday, retroactive to Sunday, according to Mark Bowman of MLB.com. It's a disappointing start to the 2026 season for Strider, but reports continue to be promising regarding his oblique injury. He will be eligible to come off the IL on April 6, although that might be a little early. Still, there's a chance that Strider will only miss a turn or two through Atlanta's starting rotation to begin the year. The 27-year-old strained his left oblique in a spring training outing last week against the Boston Red Sox. With Strider opening the year on the shelf, Jose Suarez is expected to take his rotation spot. Strider has fallen far since he won a league-high 20 games and struck out a league-high 281 batters for the Braves in 2023. He made only two starts in 2024 before having right-elbow surgery, and he didn't look the same in 23 starts last year, going 7-14 with a 4.45 ERA, 1.39 WHIP, and 131:51 K:BB in 125 1/3 innings. A drop in velocity this spring isn't encouraging for fantasy managers hoping for a bounce-back.

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As expected, the Cincinnati Reds officially announced on Wednesday that they placed left-hander Nick Lodolo (finger) on the 15-day injured list (retroactive to March 23) with a blister on his left index finger. Lodolo left his final Cactus League start last weekend with a blister issue, and as a precaution, the Reds are going to have him skip a start or two to begin the 2026 regular season. It means that all of Chase Burns, Rhett Lowder, and Brandon Williamson will be locked into the rotation to begin the year. When Lodolo returns, the Reds plan to rotate the three in the final two rotation spots due to their inexperience and recent injury history. It's a frustrating start for Lodolo, who has dealt with blister issues in the past, but he should still be rostered in all fantasy formats due to his high-strikeout upside. Barring a setback, Lodolo figures to be ready to come off the IL when he's eligible on April 7. The former seventh overall pick in 2019 out of TCU has a 26.2% strikeout rate and 6.7% walk rate in his first four big-league seasons with the Reds.

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The Houston Astros officially placed left-handed closer Josh Hader (biceps) on the 15-day injured list on Wednesday with left-biceps tendinitis, according to Brian McTaggart of MLB.com. We already knew that Hader would begin the 2026 regular season on the IL, and now it's official. The Astros haven't given a timetable for when the 31-year-old veteran southpaw will be able to make his season debut, but it could come sooner than later in April, barring a setback. Until Hader returns, right-hander Bryan Abreu should operate as the Astros' primary closer at the back end of the bullpen. Hader has been one of the most dominant fantasy closers in baseball for a while, but he was also shut down in August of last year with a left-shoulder sprain, so it's possible he could be starting to break down physically. He should take over closing duties in Houston when he comes off the IL, though, so Hader needs to be stashed in all fantasy leagues.

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The Houston Astros optioned outfield prospect Zach Cole to Triple-A Sugar Land on Wednesday, according to Chandler Rome of The Athletic. Cole loses out on the final roster spot for Opening Day to infield prospect Brice Matthews. The 25-year-old hit just .200 (8-for-40) with two home runs, five RBI, five runs scored, five stolen bases, eight walks, and 20 strikeouts in 16 Grapefruit League games this spring. The former 10th-rounder in 2022 out of Ball State made his big-league debut last year and hit .255 (12-for-47) with four home runs, 11 RBI, nine runs scored, and three steals in 15 games played. He hit .176 with a 40.5% strikeout rate in his last 37 plate appearances. Cole brings some intriguing power and speed to the table, but issues making contact could prevent him from reaching his true potential at the next level. Cole slashed .279/.377/.539 with 19 homers and 18 steals in 97 games in 2025 at Sugar Land. The left-handed-hitting outfielder is a fine stash in dynasty/keeper leagues, and we should be seeing him again in 2026 at the major-league level in a platoon outfield role.

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Houston Astros shortstop Jeremy Pena (finger) is on the team's Opening Day roster, according to Chandler Rome of The Athletic. Pena fractured the tip of his finger during an exhibition game with the Dominican Republic in a tune-up for the World Baseball Classic, but the 28-year-old has recovered nicely and was able to play in the team's exhibition game on Tuesday. He should be in the Opening Day lineup on Thursday against the division-rival Los Angeles Angels. Pena's finger injury may hinder him early on at the plate, but fantasy managers shouldn't be too worried. He was a first-time All-Star in 2025 in his fourth big-league season, slashing .304/.363/.477 with an .840 OPS, 17 home runs, 62 RBI, 68 runs scored, and 20 stolen bases in 125 games played. Pena has 30-30 upside in Houston if everything falls into place, but fantasy managers should consider him a low-end shortstop in 12-team leagues to begin 2026.

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Houston Astros infield prospect Brice Matthews has made the team's Opening Day roster, according to The Athletic's Chandler Rome. Matthews did so by hitting .250 (9-for-36) with a home run, 10 RBI, six runs scored, nine walks, and 13 strikeouts in 45 plate appearances and 16 games played this spring. The 24-year-old former first-rounder in 2023 has mostly played infield in the minors, but he has been working in the outfield during spring training and figures to open his first full year in the big leagues in a super-utility role for the Astros. Matthews made his major-league debut in 2025 and appeared in only 13 games, going 7-for-42 (.167) with four home runs, nine RBI, a stolen base, two walks, and 20 strikeouts. But at Triple-A Sugar Land, he hit 17 long balls and stole 41 bases in 498 plate appearances. The Astros are confident that Matthews is the heir apparent to Jose Altuve at the keystone in Houston. He's a high-upside rookie stash, but he'll need to make more contact to stick in the majors.

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The Los Angeles Dodgers placed left-hander Blake Snell (shoulder) on the 15-day injured list on Wednesday (retroactive to March 22) with left-shoulder fatigue, according to MLB.com. Snell dealt with left-shoulder fatigue following the team's World Series run last fall, so the Dodgers have decided to bring him along slowly this spring. The 33-year-old two-time Cy Young winner will begin the season on the shelf and isn't expected to make his 2026 season debut until late May or early June. It's a precaution after Snell missed four months in 2025 with a left-shoulder injury. Snell has begun throwing off a mound, but the Dodgers are going to ramp him up slowly so that they can have him healthy and ready to roll for the rest of the season once he returns. It's a big hit to Snell's 2026 fantasy value, but the veteran southpaw still has plenty of strikeout upside when he's healthy, making him stash-worthy in all fantasy leagues. In 11 regular-season starts with the Blue last year, Snell had a 2.35 ERA and 1.25 WHIP with 72 strikeouts and 26 walks in 61 1/3 innings pitched.

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Cincinnati Reds left-hander Brandon Williamson will open the year as the team's No. 5 starter now that left-hander Nick Lodolo (finger) is opening on the injured list, according to Rich Rovito of MLB.com. Initially, the plan was for Williamson and right-handers Chase Burns and Rhett Lowder to mix and match in the final two rotation spots to begin the 2026 campaign. Fantasy managers should temper expectations with Williamson this year after he missed all of the 2025 season due to Tommy John surgery. The 27-year-old southpaw went 5-5 with a 4.39 ERA (4.84 FIP) and 1.26 WHIP with 110 strikeouts and 44 walks in 131 1/3 innings over 27 appearances (26 starts) for the Reds in the last two seasons after debuting in the big leagues in 2023. When Lodolo makes his return, potentially after one or two turns through the team's rotation in April, Williamson could be sent to the minors or moved to a long-relief role as the Reds look to manage his workload.

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