Guest of the League
| Away | Home | Time | Away Probable | Home Probable | Status | |||
|---|---|---|---|---|---|---|---|---|
 | Orioles | at |  | Yankees | 12:05pm CT | Sugano R (10-9) | Schlittler R (3-3) | 12:05pm |
 | Cardinals | at |  | Cubs | 1:20pm CT | Liberatore L (8-12) | Taillon R (10-7) | 1:20pm |
 | Rays | at |  | Blue Jays | 2:07pm CT | Pepiot R (11-11) | Yesavage (0-0) | 2:07pm |
 | Rockies | at |  | Giants | 3:05pm CT | Freeland L (5-16) | - | 3:05pm |
 | White Sox | at |  | Nationals | 3:05pm CT | Burke R (4-11) | Cavalli R (3-1) | 3:05pm |
 | Tigers | at |  | Red Sox | 3:10pm CT | Skubal L (13-5) | Early (1-1) | 3:10pm |
 | Mets | at |  | Marlins | 3:10pm CT | Manaea L (2-4) | Perez R (7-5) | 3:10pm |
 | Twins | at |  | Phillies | 5:05pm CT | Ober R (5-9) | Suarez L (12-7) | 5:05pm |
 | Rangers | at |  | Guardians | 6:15pm CT | Corbin L (7-10) | Cecconi R (7-6) | 6:15pm |
 | Pirates | at |  | Braves | 6:15pm CT | Chandler R (3-1) | Strider R (7-13) | 6:15pm |
 | Reds | at |  | Brewers | 6:15pm CT | Abbott L (9-7) | Peralta R (17-6) | 6:15pm |
 | Diamondbacks | at |  | Padres | 7:40pm CT | Rodriguez L (9-8) | King R (5-3) | 7:40pm |
 | Astros | at |  | Angels | 8:38pm CT | Alexander R (4-2) | - | 8:38pm |
 | Dodgers | at |  | Mariners | 8:40pm CT | Glasnow R (4-3) | Gilbert R (6-6) | 8:40pm |
 | Royals | at |  | Athletics | 9:05pm CT | Wacha R (9-13) | - | 9:05pm |
