Guest of the League
Lineup Changes
3AMIGOS - HERMES GARCIA
| Started P | Patrick Sandoval (P) LAA | Owner | Mon May 6 10:35am ET |
| Benched | Jon Gray (P) TEX | Owner | Mon May 6 10:35am ET |
| Started OF | Jesse Winker (OF) WSH | Owner | Mon May 6 10:33am ET |
| Started OF | Jurickson Profar (OF) SD | Owner | Mon May 6 10:25am ET |
| Benched | Patrick Sandoval (P) LAA | Owner | Mon May 6 10:25am ET |
| Started P | Corbin Burnes (P) BAL | Owner | Mon May 6 10:25am ET |
| Started P | Emerson Hancock (P) SEA | Owner | Mon May 6 10:24am ET |
| Benched | MacKenzie Gore (P) WSH | Owner | Mon May 6 10:24am ET |
| Benched | Garrett Crochet (P) CWS | Owner | Mon May 6 10:24am ET |
| Started P | Patrick Sandoval (P) LAA | Owner | Mon May 6 10:24am ET |
| Benched | Jake Irvin (P) WSH | Owner | Mon May 6 4:26am ET |
| Started P | Jose Butto (P) NYM | Owner | Mon May 6 4:26am ET |
| Started P | Luis Gil (P) NYY | Owner | Mon May 6 4:26am ET |
| Started P | Kyle Gibson (P) STL | Owner | Mon May 6 4:26am ET |
Butt Nusters - Jake Olson
| No starting lineup changes performed this week. |
Crackerjacks - Cody Stitzel
| Benched | Andres Munoz (P) SEA | Owner | Mon May 6 10:28am ET |
| Started P | Paul Blackburn (P) OAK | Owner | Mon May 6 10:28am ET |
| Started P | Shota Imanaga (P) CHC | Owner | Mon May 6 10:28am ET |
| Benched | Carlos Rodon (P) NYY | Owner | Mon May 6 10:28am ET |
| Benched | Shota Imanaga (P) CHC | Owner | Mon May 6 10:25am ET |
| Started P | Carlos Rodon (P) NYY | Owner | Mon May 6 10:25am ET |
| Benched | Joe Musgrove (P) SD | Owner | Mon May 6 10:25am ET |
| Started P | Yu Darvish (P) SD | Owner | Mon May 6 10:25am ET |
| Benched | Michael Harris II (OF) ATL | Owner | Mon May 6 10:24am ET |
| Started OF | Tyler O'Neill (OF) BOS | Owner | Mon May 6 10:24am ET |
| Benched | Tyler O'Neill (OF) BOS | Owner | Mon May 6 10:24am ET |
| Started U | Nolan Arenado (3B) STL | Owner | Mon May 6 10:24am ET |
Daly Double - Jerry Bryant
| Started U | Vladimir Guerrero Jr. (1B) TOR | Owner | Mon May 6 3:33pm ET |
| Started OF | Taylor Ward (OF) LAA | Owner | Mon May 6 3:33pm ET |
| Benched | Taylor Ward (OF) LAA | Owner | Mon May 6 3:33pm ET |
| Benched | Jorge Soler (OF) SF | Owner | Mon May 6 3:33pm ET |
| Started 3B | Alex Bregman (3B) HOU | Owner | Mon May 6 3:32pm ET |
| Started 1B | Michael Busch (1B, 3B) CHC | Owner | Mon May 6 3:32pm ET |
| Benched | Vladimir Guerrero Jr. (1B) TOR | Owner | Mon May 6 3:32pm ET |
| Benched | Michael Busch (1B, 3B) CHC | Owner | Mon May 6 3:32pm ET |
| Benched | Brandon Pfaadt (P) ARI | Owner | Mon May 6 1:36pm ET |
| Started P | Jhoan Duran (P) MIN | Owner | Mon May 6 1:36pm ET |
| Started P | Brandon Pfaadt (P) ARI | Owner | Mon May 6 1:34pm ET |
| Benched | Evan Phillips (P) LAD | Owner | Mon May 6 1:33pm ET |
| Started P | Colin Rea (P) MIL | Owner | Mon May 6 11:29am ET |
Hillboys V - Rod Carter
| Started C | Ryan Jeffers (C) MIN | Owner | Mon May 6 8:05am ET |
| Started U | Riley Greene (OF) DET | Owner | Thu May 2 8:03am ET |
| Benched | Christopher Morel (2B, 3B, OF) CHC | Owner | Thu May 2 8:03am ET |
MOONRAKERS -
| Started P | Cristian Javier (P) HOU | Owner | Mon May 6 8:59pm ET |
| Benched | Nick Lodolo (P) CIN | Owner | Mon May 6 8:59pm ET |
| Started OF | Seiya Suzuki (OF) CHC | Owner | Mon May 6 1:37am ET |
Non losers -
| Started P | Bryse Wilson (P) MIL | Owner | Mon May 6 12:31pm ET |
| Benched | David Bednar (P) PIT | Owner | Mon May 6 12:31pm ET |
| Benched | Yusei Kikuchi (P) TOR | Owner | Mon May 6 12:29pm ET |
| Started P | David Bednar (P) PIT | Owner | Mon May 6 12:29pm ET |
| Started OF | Mark Canha (1B, OF) DET | Owner | Mon May 6 12:28pm ET |
| Benched | Mike Trout (OF) LAA | Owner | Mon May 6 12:28pm ET |
| Started P | Justin Steele (P) CHC | Owner | Sun May 5 8:40pm ET |
| Benched | Luis Severino (P) NYM | Owner | Sun May 5 8:40pm ET |
| Started P | Kyle Bradish (P) BAL | Owner | Sun May 5 8:40pm ET |
| Benched | Kenta Maeda (P) DET | Owner | Sun May 5 8:40pm ET |
PumpandDump - John Layton
| No starting lineup changes performed this week. |
The Peanuts Gang - Dean Switala
| Benched | Zach Eflin (P) TB | Owner | Mon May 6 3:02pm ET |
| Started P | Miles Mikolas (P) STL | Owner | Mon May 6 3:02pm ET |
| Started 1B | Nathaniel Lowe (1B) TEX | Owner | Mon May 6 12:42pm ET |
| Started OF | Joey Loperfido (OF) HOU | Owner | Mon May 6 12:41pm ET |
| Started P | Triston McKenzie (P) CLE | Owner | Mon May 6 12:39pm ET |
| Benched | Miles Mikolas (P) STL | Owner | Mon May 6 12:39pm ET |
| Started P | Zach Eflin (P) TB | Owner | Mon May 6 5:41am ET |
| Started U | Willy Adames (SS) MIL | Owner | Mon May 6 5:41am ET |
| Started 1B | Yandy Diaz (1B) TB | Owner | Mon May 6 5:41am ET |
| Started P | Tyler Anderson (P) LAA | Owner | Mon May 6 5:41am ET |
| Started P | Miles Mikolas (P) STL | Owner | Mon May 6 5:41am ET |
Yankees still competitive - Henry Martinez
| Benched | Trea Turner (SS) PHI | Owner | Mon May 6 3:49pm ET |
| Started U | Manny Machado (3B) SD | Owner | Mon May 6 3:49pm ET |
| Started SS | Gunnar Henderson (SS, 3B) BAL | Owner | Mon May 6 3:49pm ET |
| Benched | Gunnar Henderson (SS, 3B) BAL | Owner | Mon May 6 3:49pm ET |
| Started U | Trea Turner (SS) PHI | Owner | Mon May 6 3:49pm ET |
| Benched | Trea Turner (SS) PHI | Owner | Mon May 6 3:49pm ET |
| Started P | John Means (P) BAL | Owner | Mon May 6 3:47pm ET |
| Benched | James Paxton (P) LAD | Owner | Mon May 6 3:47pm ET |
| Benched | Jason Foley (P) DET | Owner | Sun May 5 4:48pm ET |
| Started P | Josh Hader (P) HOU | Owner | Sun May 5 4:48pm ET |
| Benched | Grayson Rodriguez (P) BAL | Owner | Sun May 5 4:45pm ET |
| Started P | Jack Flaherty (P) DET | Owner | Sun May 5 4:45pm ET |
