Guest of the League
Lineup Changes
61 -
| Benched | Nestor Cortes (P) NYY | Owner | Mon May 6 2:29am ET |
| Started P | Mitch Keller (P) PIT | Owner | Mon May 6 2:29am ET |
| Started C | Ryan Jeffers (C) MIN | Owner | Mon May 6 2:28am ET |
Apple Jacks - Tim May
| Benched | Michael Wacha (P) KC | Owner | Sun May 5 8:49pm ET |
| Started P | Luis Castillo (P) SEA | Owner | Sun May 5 8:49pm ET |
| Benched | Lourdes Gurriel Jr. (OF) ARI | Owner | Sun May 5 8:45pm ET |
| Started OF | MJ Melendez (C, OF) KC | Owner | Sun May 5 8:45pm ET |
Benched 33 -
| Started P | Kyle Harrison (P) SF | Owner | Mon May 6 12:05pm ET |
| Benched | Tanner Bibee (P) CLE | Owner | Mon May 6 12:05pm ET |
| Started P | Luis Gil (P) NYY | Owner | Mon May 6 12:05pm ET |
| Benched | Ryan Pepiot (P) TB | Owner | Mon May 6 12:05pm ET |
| Started OF | Jurickson Profar (OF) SD | Owner | Mon May 6 12:05pm ET |
| Benched | Evan Phillips (P) LAD | Owner | Mon May 6 12:04pm ET |
| Started P | Kyle Bradish (P) BAL | Owner | Mon May 6 12:04pm ET |
| Started P | Justin Steele (P) CHC | Owner | Mon May 6 12:04pm ET |
| Benched | Grayson Rodriguez (P) BAL | Owner | Mon May 6 12:04pm ET |
Blue James - James Menzies
| Started 2B | Jake Cronenworth (1B, 2B) SD | Owner | Mon May 6 12:41pm ET |
| Started C | Luis Campusano (C) SD | Owner | Mon May 6 12:41pm ET |
| Benched | Kevin Gausman (P) TOR | Owner | Mon May 6 12:39pm ET |
| Started P | Spencer Turnbull (P) PHI | Owner | Mon May 6 12:39pm ET |
CMoney25 - Craig Schlasinger
| Started P | Frankie Montas (P) CIN | Owner | Mon May 6 7:54pm ET |
| Benched | Hunter Greene (P) CIN | Owner | Mon May 6 7:54pm ET |
Crushers - Douglas Netburn
| Started OF | Brenton Doyle (OF) COL | Owner | Mon May 6 8:12am ET |
| Started U | Andy Pages (OF) LAD | Owner | Mon May 6 8:12am ET |
| Benched | Edwin Diaz (P) NYM | Owner | Mon May 6 8:12am ET |
| Started P | Jack Flaherty (P) DET | Owner | Mon May 6 8:12am ET |
| Started P | Brady Singer (P) KC | Owner | Mon May 6 7:58am ET |
| Started P | Casey Mize (P) DET | Owner | Mon May 6 7:58am ET |
| Benched | Jack Flaherty (P) DET | Owner | Mon May 6 7:58am ET |
| Benched | Nathan Eovaldi (P) TEX | Owner | Mon May 6 7:58am ET |
| Benched | Jackson Merrill (SS, OF) SD | Owner | Sun May 5 9:36pm ET |
| Started SS | Oneil Cruz (SS) PIT | Owner | Sun May 5 9:36pm ET |
| Benched | Kevin Ginkel (P) ARI | Owner | Sun May 5 9:36pm ET |
| Started P | Yu Darvish (P) SD | Owner | Sun May 5 9:36pm ET |
Fantasy Fanatic Jim - James Weiland
| Started P | Jhoan Duran (P) MIN | Owner | Sat May 4 10:47pm ET |
| Benched | Kyle Gibson (P) STL | Owner | Sat May 4 10:47pm ET |
| Started U | Wyatt Langford (OF) TEX | Owner | Sat May 4 10:46pm ET |
| Benched | Christian Encarnacion-Strand (1B) CIN | Owner | Sat May 4 10:46pm ET |
| Started 2B | Ozzie Albies (2B) ATL | Owner | Sat May 4 10:46pm ET |
| Started U | Christian Encarnacion-Strand (1B) CIN | Owner | Sat May 4 10:46pm ET |
| Benched | Ozzie Albies (2B) ATL | Owner | Sat May 4 10:46pm ET |
| Started SS | Mookie Betts (2B, SS, OF) LAD | Owner | Sat May 4 10:45pm ET |
| Benched | Mookie Betts (2B, SS, OF) LAD | Owner | Sat May 4 10:45pm ET |
| Benched | Trea Turner (SS) PHI | Owner | Sat May 4 10:45pm ET |
Last Chance Saloon -
| Started P | Nick Pivetta (P) BOS | Owner | Mon May 6 1:41am ET |
| Benched | MacKenzie Gore (P) WSH | Owner | Sun May 5 5:22pm ET |
| Started P | Cristopher Sanchez (P) PHI | Owner | Sun May 5 5:22pm ET |
| Started P | Justin Verlander (P) HOU | Owner | Sun May 5 5:22pm ET |
| Benched | Cristopher Sanchez (P) PHI | Owner | Sun May 5 5:22pm ET |
NAZGUL RIDERS - Russell Misch
| Started P | Bryse Wilson (P) MIL | Owner | Mon May 6 5:46am ET |
| Started P | Triston McKenzie (P) CLE | Owner | Mon May 6 5:46am ET |
| Started P | Logan Allen (P) CLE | Owner | Mon May 6 5:46am ET |
| Started P | Tyler Alexander (P) TB | Owner | Mon May 6 5:46am ET |
Pine Tar - Chris Watson
| No starting lineup changes performed this week. |
