| Pos | Player | Matchup | Pts | Proj | Status |
|---|---|---|---|---|---|
| Starters9 | |||||
| QB |  Joe BurrowCIN Bye 6 |
TBSun 1:00pm ET | 0.00 | 21.70 | Starter |
| RB |  Devon AchaneMIA Bye 6 |
@LVSun 4:25pm ET | 0.00 | 18.10 | Starter |
| RB |  Saquon BarkleyPHI Bye 10 |
WASSun 4:25pm ET | 0.00 | 16.10 | Starter |
| WR |  Justin JeffersonMIN Bye 6 |
GBSun 4:25pm ET | 0.00 | 16.40 | Starter |
| WR |  CeeDee LambDAL Bye 14 |
@NYGSun 8:20pm ET | 0.00 | 17.00 | Starter |
| WR |  Amon-Ra St. BrownDET Bye 6 |
NOSun 1:00pm ET | 0.00 | 18.60 | Starter |
| TE |  Tucker KraftGB Bye 11 |
@MINSun 4:25pm ET | 0.00 | 10.60 | Starter |
| K |  Will ReichardMIN Bye 6 |
GBSun 4:25pm ET | 0.00 | 8.46 | Starter |
| D/ST |  Detroit LionsDET Bye 6 |
NOSun 1:00pm ET | 0.00 | 5.00 | Starter |
| Bench13 | |||||
| QB |  Jared GoffDET Bye 6 |
NOSun 1:00pm ET | 0.00 | 19.00 | Bench |
| RB |  LeQuint AllenJAX Bye 7 |
CLESun 1:00pm ET | 0.00 | 3.80 | Bench |
| RB |  TreVeyon HendersonNE Bye 11 |
@SEAWed 8:20pm ET | 0.00 | 9.50 | Bench |
| RB |  Bucky IrvingTB Bye 10 |
@CINSun 1:00pm ET | 0.00 | 12.70 | Bench |
| RB |  Damien MartinezGB Bye 11 |
@MINSun 4:25pm ET | 0.00 | 0.00 | Bench |
| RB |  Rachaad WhiteWAS Bye 7 |
@PHISun 4:25pm ET | 0.00 | 9.60 | Bench |
| WR |  Keenan AllenIND Bye 13 |
BALSun 1:00pm ET | 0.00 | 7.20 | Bench |
| WR |  Tank DellHOU Bye 8 IR |
BUFSun 1:00pm ET | 0.00 | 2.70 | Bench |
| WR |  Troy FranklinDEN Bye 10 |
@KCMon 8:15pm ET | 0.00 | 2.60 | Bench |
| WR |  Jayden HigginsHOU Bye 8 IR |
BUFSun 1:00pm ET | 0.00 | 0.00 | Bench |
| WR |  Ladd McConkeyLAC Bye 7 |
ARISun 4:25pm ET | 0.00 | 13.00 | Bench |
| WR |  Christian WatsonGB Bye 11 |
@MINSun 4:25pm ET | 0.00 | 12.10 | Bench |
| TE |  Harold Fannin Jr.CLE Bye 11 |
@JAXSun 1:00pm ET | 0.00 | 11.40 | Bench |
