Mike Trout hit a leadoff home run and the Los Angeles Angels ended a five-game losing streak with a 7-4 win against the visiting Baltimore Orioles in the second game of a three-game series on Tuesday night.

The bottom four hitters in the Los Angeles lineup -- Logan O'Hoppe, Jo Adell, Luis Rengifo and Zach Neto -- combined to go 8-for-14 with five runs and five RBIs.

Angels starter Griffin Canning (1-3) allowed three runs and five hits in five innings. He struck out four and walked two.

Adam Cimber pitched a scoreless sixth. Luis Garcia threw 1 2/3 scoreless innings and Carlos Estevez pitched the ninth for his fourth save of the season.

Gunnar Henderson hit a solo homer and drove in two runs, and Adley Rutschman had three hits and a run scored for Baltimore, which had won three straight and seven of eight.

Orioles starter Grayson Rodriguez (3-1) allowed seven runs and 11 hits in 4 1/3 innings. He struck out seven and walked one.

Trout hit a 1-2 pitch to right-center field for his first leadoff home run since 2012, giving the Angels a 1-0 lead.

Adell and Rengifo had back-to-back one-out doubles in the second to make it 2-0. Neto followed with a single to right to drive in Rengifo for a 3-0 lead.

Taylor Ward doubled off the wall on the first pitch of the third before O'Hoppe delivered a two-out RBI double down the left-field line to make it 4-0. Adell followed with an RBI single to center for a 5-0 lead.

Rengifo led off the fourth with an infield single and scored from first on a double into the left-field corner by Neto to make it 6-0.

Neto moved to third on a flyout and scored on a line-drive single to right by Nolan Schanuel for a 7-0 lead.

Canning retired seven straight hitters before the first two batters reached in the fourth on a single and a walk. After a mound visit, Canning retired the next three.

A single by Orioles rookie Jackson Holliday put runners on the corners with one out in the fifth. After a sacrifice fly cut it to 7-1, the Orioles put runners back on the corners and Ryan O'Hearn delivered a two-strike, two-run double to left field to make it 7-3.

Henderson hit a solo shot off Matt Moore in the seventh to trim the deficit to 7-4.